Search Result "positive allosteric modulation efficacy"


Allosteric Modulators for mGlu Receptors

Journal: Current Neuropharmacology
Volume: 5 Issue: 3 Year: 2007 Page: 187-194
Author(s): F. Gasparini, W. Spooren

Positive Allosteric Modulators for mGluR2 Receptors: A Medicinal Chemistry Perspective

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 15 Year: 2014 Page: 1771-1788
Author(s): Gyorgy Szabo,Gyorgy Miklos Keseru

Discovery of Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 (mGluR5)

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 9 Year: 2005 Page: 825-846
Author(s): David L. Williams Jr., Craig W. Lindsley

Advances in the Discovery of Novel Positive Allosteric Modulators of the α7 Nicotinic Acetylcholine Receptor

Journal: Recent Patents on CNS Drug Discovery (Discontinued)
Volume: 2 Issue: 2 Year: 2007 Page: 99-106
Author(s): Ramin Faghih, Gregory A. Gfesser, Murali Gopalakrishnan

Desformylflustrabromine: A Novel Positive Allosteric Modulator for beta2 Subunit Containing Nicotinic Receptor Sub-Types

Journal: Current Pharmaceutical Design
Volume: 22 Issue: 14 Year: 2016 Page: 2057-2063
Author(s): Anshul A. Pandya

SAR Studies on Carboxylic Acid Series M1 Selective Positive Allosteric Modulators (PAMs)

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 15 Year: 2014 Page: 1738-1754
Author(s): Scott D. Kuduk,Douglas C. Beshore

Letter Article open access plus

Challenges in the Discovery and Optimization of mGlu2/4 Heterodimer Positive Allosteric Modulators

Journal: Letters in Drug Design & Discovery
Volume: 16 Issue: 12 Year: 2019 Page: 1387-1394
Author(s): Mark Gallant Fulton,Matthew Thomas Loch,Caroline Anne Cuoco,Alice Lambert Rodriguez,Emily Days,Paige Newton Vinson,Krystian Andrezej Kozek,Charles David Weaver,Anna Louise Blobaum,Peter Jeffrey Conn,Colleen Marie Niswender,Craig William Lindsley

Progress in the Developement of Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 2

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 47-68
Author(s): A. A. Trabanco, J. M. Cid, H. Lavreysen, G. J. Macdonald, G. Tresadern

Review Article

AMPA Receptor Positive Allosteric Modulators: Potential for the Treatment of Neuropsychiatric and Neurological Disorders

Journal: Current Topics in Medicinal Chemistry
Volume: 16 Issue: 2 Year: 2016 Page: 3536-3565
Author(s): Tristan Reuillon, Simon E. Ward, Paul Beswick

Review Article

Tuning Down the Pain – An Overview of Allosteric Modulation of Opioid Receptors: Mechanisms of Modulation, Allosteric Sites, Modulator Syntheses

Journal: Current Topics in Medicinal Chemistry
Volume: 20 Issue: 31 Year: 2020 Page: 2852-2865
Author(s): Damian Bartuzi,Tomasz M. Wróbel,Agnieszka A. Kaczor,Dariusz Matosiuk

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