Search Result "off-target effects."


RNAi and Off-Target Effects

Ebook: Frontiers in RNAi
Volume: 1 Year: 2014
Author(s): Amanda Birmingham,Andreas Kaufmann,Karol Kozak
Doi: 10.2174/9781608059409114010005

Research Article

Prediction of Off-Target Effects in CRISPR/Cas9 System by Ensemble Learning

Journal: Current Bioinformatics
Volume: 16 Issue: 9 Year: 2021 Page: 1169-1178
Author(s): Yongxian Fan,Haibo Xu

Research Article

Recognition of CRISPR Off-Target Cleavage Sites with SeqGAN

Journal: Current Bioinformatics
Volume: 17 Issue: 1 Year: 2022 Page: 101-107
Author(s): Wen Li,Xiao-Bo Wang,Yan Xu

Morpholino, siRNA, and S-DNA Compared: Impact of Structure and Mechanism of Action on Off-Target Effects and Sequence Specificity

Journal: Current Topics in Medicinal Chemistry
Volume: 7 Issue: 7 Year: 2007 Page: 651-660
Author(s): James E. Summerton

Recent Advances in Understanding of the Immunological Off-Target Effects of siRNA

Journal: Current Gene Therapy
Volume: 11 Issue: 6 Year: 2011 Page: 532-543
Author(s): Marta Olejniczak, Katarzyna Polak, Paulina Galka-Marciniak, Wlodzimierz J. Krzyzosiak

Update on ICOS: A Possible Target for Turning-Off Autoimmunity

Journal: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Volume: 3 Issue: 3 Year: 2009 Page: 205-213
Author(s): Priya Sakthivel

Review Article

CRISPR/ Cas9 Off-targets: Computational Analysis of Causes, Prediction,Detection, and Overcoming Strategies

Journal: Current Bioinformatics
Volume: 17 Issue: 2 Year: 2022 Page: 119-132
Author(s): Roshan Kumar Roy,Ipsita Debashree,Sonal Srivastava,Narayan Rishi,Ashish Srivastava

Review Article

Oxidative Status in Multiple Sclerosis and Off-Targets of Antioxidants: The Case of Edaravone

Journal: Current Medicinal Chemistry
Volume: 27 Issue: 13 Year: 2020 Page: 2095-2105
Author(s): Cristina Agresti,Rosella Mechelli,Stefania Olla,Caterina Veroni,Cecilia Eleuteri,Giovanni Ristori,Marco Salvetti

Mechanisms of Action of DNA-Damaging Anticancer Drugs in Treatment of Carcinomas: Is Acute Apoptosis an “Off-Target” Effect?

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 7 Issue: 1 Year: 2007 Page: 1035-1039
Author(s): Aleksandra Mandic Havelka, Maria Berndtsson, Maria Hagg Olofsson, Maria C. Shoshan, Stig Linder

Blind Snipers: Relevant Off Target Effects of Non-chemotherapeutic Agents in Oncology: Review of the Literature

Journal: Reviews on Recent Clinical Trials
Volume: 9 Issue: 2 Year: 2014 Page: 102-114
Author(s): Tiziana Prochilo,Brunella Di Biasi,Francesca Aroldi,Paola Bertocchi,Tony Sabatini,Fausto Meriggi,Alberto Zaniboni

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