Search Result "hits prioritization"


A Simple Method for Analyzing Actives in Random RNAi Screens: Introducing the “H Score” for Hit Nomination & Gene Prioritization

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 15 Issue: 9 Year: 2012 Page: 686-704
Author(s): Bhavneet Bhinder,Hakim Djaballah

A Collaborative Hit-to-Lead Investigation Leveraging Medicinal Chemistry Expertise with High Throughput Library Design, Synthesis and Purification Capabilities

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 123-130
Author(s): X. Yang, D. Parker, L. Whitehead, N. S. Ryder, B. Weidmann, M. Stabile-Harris, D. Kizer, M. McKinnon, A. Smellie, D. Powers

Target Immobilization and NMR Screening of Fragments in Early Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 1736-1745
Author(s): Gregg Siegal, Johan G. Hollander

NMR Screening and Hit Validation in Fragment Based Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 43-67
Author(s): Ramon Campos-Olivas

Ligand and Structure Based Virtual Screening Strategies for Hit-Finding and Optimization of Hepatitis C Virus (HCV) Inhibitors

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 2612-2619
Author(s): G. Melagraki, A. Afantitis

Integrity Profiling of High Throughput Screening Hits Using LC-MS and Related Techniques

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 8 Issue: 6 Year: 2005 Page: 459-466
Author(s): Edward H. Kerns, Li Di, Jim Bourassa, Jonathan Gross, Nelson Huang, Hanlan Liu, Teresa Kleintop, Lisa Nogle, Larry Mallis, Chris Petucci, Susan Petusky, Mark Tischler, Chantel Sabus, Ani Sarkahian, Mairead Young, Mei-yi Zhang, Donna Huryn, Oliver McConnell, Guy Carter

Rational Design Approaches to Chemical Libraries for Hit Identification

Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 1 Year: 2006 Page: 49-65
Author(s): Konstantin V. Balakin, Alexander V. Kozintsev, Alex S. Kiselyov, Nikolay P. Savchuk

Extraction of Structure-Activity Relationship Information from High-Throughput Screening Data

Journal: Current Medicinal Chemistry
Volume: 16 Issue: 3 Year: 2009 Page: 4049-4057
Author(s): M. Wawer, J. Bajorath

The CellCard(™) System: A Novel Approach to Assessing Compound Selectivity for Lead Prioritization of G Protein-Coupled Receptors

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 8 Issue: 4 Year: 2005 Page: 293-299
Author(s): Oren Beske, Simon Goldbard, Pierre Turpin

High Throughput Screening for Neurodegeneration and Complex Disease Phenotypes

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 11 Issue: 3 Year: 2008 Page: 238-248
Author(s): Hemant Varma, Donald C. Lo, Brent R. Stockwell

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