Search Result "fragmental topology-activity landscape"


Probing a Chemical Space for Fragmental Topology-Activity Landscapes (FRAGTAL): Application for Diketo Acid and Catechol HIV Integrase Inhibitor Offspring Fragments

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 16 Issue: 4 Year: 2013 Page: 274-287
Author(s): Andrzej Bak,Tomasz Magdziarz,Agata Kurczyk,Katarzyna Serafin,Jaroslaw Polanski

Review Article

IgG Fc Fragment as a Scaffold for Development of Targeted Therapeutics

Journal: Current Pharmaceutical Biotechnology
Volume: 17 Issue: 15 Year: 2016 Page: 1315-1323
Author(s): Gordana W. Knopp,Gerhard Stadlmayr,Florian Ruker

Fragment-Based Drug Design: Computational and Experimental State of the Art

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 14 Issue: 6 Year: 2011 Page: 500-520
Author(s): Laurent Hoffer, Jean-Paul Renaud, Dragos Horvath

Computational Approaches for Fragment-Based and De Novo Design

Journal: Current Topics in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 14-32
Author(s): Kathryn Loving, Ian Alberts, Woody Sherman

Combinatorial Chemistry and Fragment Screening - Two Unlike Siblings?

Journal: Current Drug Discovery Technologies
Volume: 2 Issue: 1 Year: 2005 Page: 1-12
Author(s): Hans Peter Nestler

Fragment-Based Optimization of Small Molecule CXCL12 Inhibitors for Antagonizing the CXCL12/CXCR4 Interaction

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 2 Year: 2012 Page: 2727-2740
Author(s): Joshua J. Ziarek, Yan Liu, Emmanuel Smith, Guolin Zhang, Francis C. Peterson, Jun Chen, Yongping Yu, Yu Chen, Brian F. Volkman, Rongshi Li

Graph Theory Concepts in the Rationales of Anti HIV-1 Compounds

Journal: Current Computer-Aided Drug Design
Volume: 9 Issue: 4 Year: 2013 Page: 472-481
Author(s): Utsab Debnath,Seturam B. Katti,Yenamandra S. Prabhakar

Research Article

Piecing the Fragments Together: Dynamical Insights into the Enhancementof BRD4-BD1 (BET Protein) Druggability in Cancer ChemotherapyUsing Novel 8-methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one Derivatives

Journal: Current Pharmaceutical Biotechnology
Volume: 23 Issue: 3 Year: 2022 Page: 444-456
Author(s): Oluwole B. Akawa,Opeyemi S. Soremekun,Fisayo A. Olotu,Mahmoud E.S. Solima

Conformational Landscape of the Nucleoside Reverse Transcriptase Inhibitor d4T: a Comprehensive Quantum-Chemical Approach

Journal: Current Physical Chemistry
Volume: 3 Issue: 1 Year: 2013 Page: 83-92
Author(s): Alla G. Ponomareva,Yevgen P. Yurenko,Roman O. Zhurakivsky,Tanja van Mourik,Dmytro M. Hovorun

Quantitative Structure-Activity Relationships for Anticancer Activity of 2- Phenylindoles Using Mathematical Molecular Descriptors

Journal: Current Computer-Aided Drug Design
Volume: 7 Issue: 2 Year: 2011 Page: 98-108
Author(s): Subhash C. Basak, Qianhong Zhu, Denise Mills

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