Search Result "Unbound fraction"


The Role of Unbound Drug in Pharmacokinetics/Pharmacodynamics and in Therapy

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 8 Year: 2006 Page: 977-987
Author(s): Rosario Calvo, John C. Lukas, Monica Rodriguez, Nerea Leal, Elena Suarez

Integration Over Unbounded Regions

Ebook: Advanced Calculus Fundamentals of Mathematics
Volume: 1 Year: 2019
Author(s): Carlos Polanco
Doi: 10.2174/97898114150811190101

Insight into Tissue Unbound Concentration: Utility in Drug Discovery and Development

Journal: Current Drug Metabolism
Volume: 14 Issue: 3 Year: 2013 Page: 324-340
Author(s): T. Thanga Mariappan,Sandhya Mandlekar,Punit Marathe

Research Article

Liquid Chromatography-Tandem Mass Spectrometry to Monitor Unbound and Total Ceftriaxone in Serum of Critically Ill Patients

Journal: Current Clinical Pharmacology
Volume: 15 Issue: 0 Year: 2020 Page: 1-10
Author(s): Sjoerd Meenks,Jos le Noble,Norbert Foudraine,Frank de Vries,Paddy Janssen

In Silico Prediction of Brain Exposure: Drug Free Fraction, Unbound Brain to Plasma Concentration Ratio and Equilibrium Half-Life

Journal: Current Topics in Medicinal Chemistry
Volume: 13 Issue: 7 Year: 2013 Page: 813-820
Author(s): Morena Spreafico, Matthew P. Jacobson

Fractionation Techniques Improve the Proteomic Analysis of Human Serum

Journal: Current Pharmaceutical Analysis
Volume: 4 Issue: 2 Year: 2008 Page: 69-77
Author(s): Pierluigi Mauri, Andrea Petretto, Davide Cuccabita, Fabrizio Basilico, Dario Di Silvestre, Isabella Levreri, Giovanni Melioli

Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 450-466
Author(s): Xingrong Liu, Cuiping Chen, Cornelis E.C.A. Hop

Review Article

Molecular Modeling Approaches for the Prediction of Selected Pharmacokinetic Properties

Journal: Current Topics in Medicinal Chemistry
Volume: 18 Issue: 26 Year: 2018 Page: 2230-2238
Author(s): Emilio S. Petito,David J.R. Foster,Michael B. Ward,Matthew J. Sykes

Nucleoprotein-Derived and Unbound Ribonucleosides: Bioactivity and Potential Applications

Journal: Current Pharmaceutical Design
Volume: 13 Issue: 9 Year: 2007 Page: 921-932
Author(s): Dierk Martin, Hans Meisel

CSF as a Surrogate for Assessing CNS Exposure: An Industrial Perspective

Journal: Current Drug Metabolism
Volume: 9 Issue: 1 Year: 2008 Page: 46-59
Author(s): Jiunn H. Lin

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