Search Result "Sirt2"


Research Article

Discovery of Potent Natural-Product-Derived SIRT2 Inhibitors Using Structure- Based Exploration of SIRT2 Pharmacophoric Space Coupled With QSAR Analyses

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 21 Issue: 16 Year: 2021 Page: 2278-2286
Author(s): Mohammad A. Khanfar,Saja Alqtaishat

Review Article

Recent Progress on the Discovery of Sirt2 Inhibitors for the Treatment of Various Cancers

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 12 Year: 2019 Page: 1051-1058
Author(s): Ting Wang,Zhuyu Xu,Yongping Lu,Jianyou Shi,Wenbo Liu,Chengchen Zhang,Zhongliang Jiang,Baowen Qi,Lan Bai

Research Article

Exploring and Designing Potential Inhibitors of SIRT2 in Natural Products by Artificial Intelligence (AI) and Molecular Dynamics Methods

Journal: Letters in Drug Design & Discovery
Volume: 21 Issue: 16 Year: 2024 Page: 3542-3554
Author(s):

Research Article

Affinity Prediction of Shikonins Towards Sirtuins and the Requisite Structural Motifs for the Selective Inhibition of SIRT2 and SIRT3

Journal: Letters in Drug Design & Discovery
Volume: 21 Issue: 4 Year: 2024 Page: 724-737
Author(s):

open access plus

Selective Inhibition of SIRT2 Improves Outcomes in a Lethal Septic Model

Journal: Current Molecular Medicine
Volume: 15 Issue: 7 Year: 2015 Page: 634-641
Author(s): T. Zhao,H.B. Alam,B. Liu,R.T. Bronson,V.C. Nikolian,E. Wu,W. Chong,Y. Li

Research Article

Interpretable SMILES-based QSAR Model of Inhibitory Activity of Sirtuins 1 and 2

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 24 Issue: 8 Year: 2021 Page: 1217-1228
Author(s): Apilak Worachartcheewan,Alla P. Toropova,Andrey A. Toropov,Reny Pratiwi,Virapong Prachayasittikul,Chanin Nantasenamat

Current Advances in the Synthesis and Antitumoral Activity of SIRT1-2 Inhibitors by Modulation of p53 and Pro-Apoptotic Proteins

Journal: Current Medicinal Chemistry
Volume: 19 Issue: 34 Year: 2012 Page: 5871-5884
Author(s): G. Botta,L. P. De Santis,R. Saladino

Cytotoxicity and Cell Death Mechanisms Induced by a Novel Bisnaphthalimidopropyl Derivative against the NCI-H460 non-small Lung Cancer Cell Line

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 13 Issue: 3 Year: 2013 Page: 414-421
Author(s): Raquel T. Lima,Gemma A. Barron,Joanna A. Grabowska,Giovanna Bermano,Simranjeet Kaur,Nilanjan Roy,M. Helena Vasconcelos,Paul K.T. Lin

Rejuvenating Sirtuins: The Rise of a New Family of Cancer Drug Targets

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 4 Year: 2013 Page: 614-623
Author(s): Santina Bruzzone, Marco Daniele Parenti, Alessia Grozio, Alberto Ballestrero, Inga Bauer, Alberto Del Rio, Alessio Nencioni

Advances in Characterization of Human Sirtuin Isoforms: Chemistries, Targets and Therapeutic Applications

Journal: Current Medicinal Chemistry
Volume: 18 Issue: 1 Year: 2011 Page: 1919-1935
Author(s): Y. Cen, D. Y. Youn, A. A. Sauve

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