Search Result "Multi Target Drug Ligands (MTDLs)"


The Development of Multi-Target-Directed Ligands (MTDL) to Treat Alzheimer’s Disease

Ebook: Frontiers in Clinical Drug Research - Alzheimer Disorders
Volume: 1 Year: 2013
Author(s): John W. Wright,Joseph W. Harding
Doi: 10.2174/9781608057221113010004

Review Article

Multi-Target-Directed Ligands as an Effective Strategy for the Treatment of Alzheimer’s Disease

Journal: Current Medicinal Chemistry
Volume: 29 Issue: 10 Year: 2022 Page: 1757-1803
Author(s): Vinod Kumar,Ashish Ranjan Dwivedi,Amandeep Thakur,Bhupinder Kumar

Review Article

Changing Paradigm from one Target one Ligand Towards Multi-target Directed Ligand Design for Key Drug Targets of Alzheimer Disease: An Important Role of In Silico Methods in Multi-target Directed Ligands Design

Journal: Current Neuropharmacology
Volume: 16 Issue: 6 Year: 2018 Page: 726-739
Author(s): Akhil Kumar,Ashish Tiwari,Ashok Sharma

MTDL Design Strategy in the Context of Alzheimers Disease: From Lipocrine to Memoquin and Beyond

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 6 Year: 2009 Page: 601-613
Author(s): M. L. Bolognesi, M. Rosini, V. Andrisano, M. Bartolini, A. Minarini, V. Tumiatti, C. Melchiorre

Review Article

Therapeutic Agents in Alzheimer's Disease Through a Multi-targetdirected Ligands Strategy: Recent Progress Based on Tacrine Core

Journal: Current Topics in Medicinal Chemistry
Volume: 17 Issue: 27 Year: 2017 Page: 3000-3016
Author(s): Hongzhi Lin,Qi Li,Kai Gu,Jie Zhu,Xueyang Jiang,Yao Chen,Haopeng Sun

Review Article

Applications of Multi-Target Computer-Aided Methodologies in Molecular Design of CNS Drugs

Journal: Current Medicinal Chemistry
Volume: 25 Issue: 3 Year: 2018 Page: 5293-5314
Author(s): Oleg A. Raevsky,Azat Mukhametov,Veniamin Y. Grigorev,Alexey Ustyugov,Shwu-Chen Tsay,Reuben Jih-Ru Hwu,Nagendra Sastry Yarla,George E. Barreto,Gjumrakch Aliev,Sergey O Bachurin

Review Article

Docking Studies for Multi-Target Drugs

Journal: Current Drug Targets
Volume: 18 Issue: 5 Year: 2017 Page: 592-604
Author(s): Luciana Scotti,Francisco J.B. Mendonca Junior,Hamilton M. Ishiki,Frederico F. Ribeiro,Rajeev K. Singla,Jose M. Barbosa Filho,Marcelo S. Da Silva,Marcus T. Scotti

From Dual Binding Site Acetylcholinesterase Inhibitors to Multi-Target-Directed Ligands (MTDLs): A Step Forward in the Treatment of Alzheimers Disease

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 1 Year: 2008 Page: 960-967
Author(s): Maria Laura Bolognesi, Anna Minarini, Michela Rosini, Vincenzo Tumiatti, Carlo Melchiorre

Review Article

The Emerging Role of COX-2, 15-LOX and PPARγ in Metabolic Diseases and Cancer: An Introduction to Novel Multi-target Directed Ligands (MTDLs)

Journal: Current Medicinal Chemistry
Volume: 28 Issue: 11 Year: 2021 Page: 2260-2300
Author(s): Rana A. Alaaeddine,Perihan A. Elzahhar,Ibrahim AlZaim,Wassim Abou-Kheir,Ahmed S.F. Belal,Ahmed F. El-Yazbi

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