Search Result "Lipinski`s rule of five."


Lipinski’s Rule of Five

Ebook: 2-Deoxy-D-Glucose: Chemistry and Biology
Volume: 1 Year: 2024
Author(s):
Doi: 10.2174/9789815305159124010015

Research Article

Analysis of the Applicability and Use of Lipinski`s Rule for Central Nervous System Drugs

Journal: Letters in Drug Design & Discovery
Volume: 13 Issue: 1 Year: 2016 Page: 999-1006
Author(s): Thais B. Fernandes, Mariana C. F. Segretti, Michelle C. Polli, Roberto Parise-Filho

Research Article

Withania somnifera Phytochemicals Confer Neuroprotection by Inhibition of the Catalytic Domain of Human Matrix Metalloproteinase-9

Journal: Letters in Drug Design & Discovery
Volume: 14 Issue: 6 Year: 2017 Page: 718-726
Author(s): Gaurav Kumar,Pankaj Paliwal,Ranjana Patnaik

Review Article

Description and In silico ADME Studies of US-FDA Approved Drugs orDrugs under Clinical Trial which Violate the Lipinski’s Rule of 5

Journal: Letters in Drug Design & Discovery
Volume: 21 Issue: 8 Year: 2024 Page: 1334-1358
Author(s): Ankit Kumar Singh,Jagat Pal Yadav

Research Article

New SARS-CoV-2 Mpro Inhibitor by Ascorbic Acid: Design, MolecularDocking, Lipinski’s Rule and ADMET Analysis

Journal: Coronaviruses
Volume: 5 Issue: 1 Year: 2024 Page: 13-52
Author(s): Abdulrahman Salman Alazmi

General Research Article

Structure-based Virtual Screening, Molecular Docking, MolecularDynamics Simulation, and Metabolic Reactivity Studies ofQuinazoline Derivatives for their Anti-EGFR Activity AgainstTumor Angiogenesis

Journal: Current Medicinal Chemistry
Volume: 31 Issue: 5 Year: 2024 Page: 595-619
Author(s): Altaf Ahmad Shah,Manoj Kumar Yadav,Mohammad Amjad Kamal

Research Article

Synthesis, In silico Molecular Docking and Pharmacokinetic Studies, In vitro Antimycobacterial and Antimicrobial Studies of New Imidozolones Clubbed with Thiazolidinedione

Journal: Current Computer-Aided Drug Design
Volume: 14 Issue: 4 Year: 2018 Page: 269-283
Author(s): Imran. H. Khan,Navin B. Patel,Vatsal M. Patel

Design, Synthesis and Evaluation of Unique 2,4,5-triaryl Imidazole Derivatives as Novel Potent Aspartic Protease Inhibitors

Journal: Medicinal Chemistry
Volume: 8 Issue: 3 Year: 2012 Page: 428-435
Author(s): Mohd Sajid Khan,Salman Akhtar,S. A. Siddiqui,M. S. Siddiqui,K. V. Srinivasan,J. M. Arif

Review Article

The use of Sulfonamide Derivatives in the Treatment of Trypanosomatid Parasites including Trypanosoma cruzi, Trypanosoma brucei, and Leishmania ssp

Journal: Medicinal Chemistry
Volume: 16 Issue: 1 Year: 2020 Page: 24-38
Author(s): Cauê B. Scarim,Rafael C. Chelucci,Jean L. dos Santos,Chung M. Chin

Quantitative Measurement of Some Physico-Chemical Parameters for the Medicinally Useful Natural Products

Journal: Letters in Drug Design & Discovery
Volume: 9 Issue: 7 Year: 2012 Page: 706-730
Author(s): Koyel Kar,Aditya Sethi,D. Archana,S. Vasavi,P. Maheswari,P. Niranjini,L. Vimalacharitha,W. Prathyusha,V. Sai Thanuja,K. Sreejana Reddy,G. Rohith,Amnish Kumar,A. G. Damodar,B. R. Prashantha Kumar

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