Search Result "CPT-11 metabolism"


Therapeutic Targeting of CPT-11 Induced Diarrhea: A Case for Prophylaxis

Journal: Current Drug Targets
Volume: 14 Issue: 7 Year: 2013 Page: 777-797
Author(s): Umang Swami, Sanjay Goel, Sridhar Mani

Pharmacology of Topoisomerase I Inhibitors Irinotecan (CPT-11) and Topotecan

Journal: Current Cancer Drug Targets
Volume: 2 Issue: 2 Year: 2002 Page: 103-123
Author(s): Ron H.J. Mathijssen, Walter J. Loos, Jaap Verweij, Alex Sparreboom

Research Article

Enzyme and Transporter Kinetics for CPT-11 (Irinotecan) and SN-38: An Insight on Tumor Tissue Compartment Pharmacokinetics Using PBPK

Journal: Recent Patents on Anti-Cancer Drug Discovery
Volume: 14 Issue: 2 Year: 2019 Page: 177-186
Author(s): Yingfang Fan,Najia Mansoor,Tasneem Ahmad,Zhuo X. Wu,Rafeeq A. Khan,Martin Czejka,Syed Sharib,Mansoor Ahmed,Zhe S. Chen,Dong H. Yang

Pharmacokinetic Mechanisms for Reduced Toxicity of Irinotecan by Coadministered Thalidomide

Journal: Current Drug Metabolism
Volume: 7 Issue: 4 Year: 2006 Page: 431-454
Author(s): Xiao-Xia Yang, Ze-Ping Hu, Sui Y. Chan, Wei Duan, Paul C.-L. Ho, Urs A. Boelsterli, Ka-Yun Ng, Eli Chan, Jin-Song Bian, Yu-Zong Chen, Min Huang, > Zhou

Research Article

Substrate-dependent Inhibition of Hypericin on Human Carboxylesterase 2: Implicationsfor Herb-drug Combination

Journal: Current Drug Metabolism
Volume: 23 Issue: 1 Year: 2022 Page: 38-44
Author(s):

Effective Prodrug Liposome and Conversion to Active Metabolite

Journal: Current Drug Metabolism
Volume: 1 Issue: 1 Year: 2000 Page: 31-48
Author(s): Y. Sadzuka

Transport Mechanism-Based Drug Molecular Design: Novel Camptothecin Analogues to Circumvent ABCG2-associated Drug Resistance of Human Tumor Cells

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 3 Year: 2006 Page: 313-325
Author(s): Toshihisa Ishikawa, Yoji Ikegami, Kazumi Sano, Hiroshi Nakagawa, Seigo Sawada

Novel Agents that Potentially Inhibit Irinotecan-Induced Diarrhea

Journal: Current Medicinal Chemistry
Volume: 12 Issue: 1 Year: 2005 Page: 1343-1358
Author(s): Xiaoxia Yang, Zeping Hu, Sui Yung Chan, Eli Chan, Boon Cher Goh, Wei Duan, Shufeng Zhou

Metabolic Therapy of Heart Failure

Journal: Current Pharmaceutical Design
Volume: 14 Issue: 2 Year: 2008 Page: 2582-2591
Author(s): Gabriele Fragasso, Anna Salerno, Roberto Spoladore, Giorgio Bassanelli, Francesco Arioli, Alberto Margonato

ABCB1, SLCO1B1 and UGT1A1 Gene Polymorphisms Are Associated with Toxicity Line Irinotecan

Journal: Drug Metabolism Letters
Volume: 1 Issue: 1 Year: 2007 Page: 23-30
Author(s): Katrin E. Rhodes, Wu Zhang, Dongyun Yang, Oliver A. Press, Michael Gordon, Daniel Vallbohmer, Anne M. Schultheis, Georg Lurje, Robert D. Ladner, William Fazzone, Heinz-Josef Lenz, Syma Iqbal

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