Search Result "nonleadlike"

False Positives in the Early Stages of Drug Discovery

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2010 Page: 4231-4255
Author(s): R. Sink, S. Gobec, S. Pecar, A. Zega

Failure and Success in Modern Drug Discovery: Guiding Principles in the Establishment of High Probability of Success Drug Discovery Organizations

Journal: Medicinal Chemistry
Volume: 1 Issue: 5 Year: 2005 Page: 519-527
Author(s): G. M. Rishton

Discovery of ADDL-Targeting Small Molecule Drugs for Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 4 Issue: 5 Year: 2007 Page: 562-567
Author(s): Gary C. Look, Jasna Jerecic, Diana B. Cherbavaz, Todd R. Pray, Jean-Claude R. Breach, Walter J. Crosier, Lev Igoudin, Catherine M. Hironaka, Raymond M. Lowe, Michele McEntee, Lily Ruslim-Litrus, Hsiu-Mei Wu, Sue Zhang, Susan M. Catalano, William F. Goure, David Summa, Grant A. Krafft

Multivariate Linear Regression Models Based on ADME Descriptors and Predictions of ADMET Profile for Structurally Diverse Thermolysin Inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 6 Issue: 6 Year: 2009 Page: 428-436
Author(s): Mahmud Tareq Hassan Khan, Ingebrigt Sylte

Open Innovation Drug Discovery (OIDD): A Potential Path to Novel Therapeutic Chemical Space

Journal: Current Topics in Medicinal Chemistry
Volume: 14 Issue: 3 Year: 2014 Page: 294-303
Author(s): Maria Alvim-Gaston, Timothy Grese, Abdelaziz Mahoui, Alan D. Palkowitz, Marta Pineiro-Nunez, Ian Watson

NMR-Based Quality Control Approach for the Identification of False Positives and False Negatives in High Throughput Screening

Journal: Current Drug Discovery Technologies
Volume: 3 Issue: 2 Year: 2006 Page: 115-124
Author(s): Claudio Dalvit, Dannica Caronni, Nicola Mongelli, Marina Veronesi, Anna Vulpetti

Solution Stability - Plasma, Gastrointestinal, Bioassay

Journal: Current Drug Metabolism
Volume: 9 Issue: 9 Year: 2008 Page: 860-868
Author(s): Li Di, Edward H. Kerns

Design and Development of Signal Transduction Inhibitors for Cancer Treatment: Experience and Challenges with Kinase Targets

Journal: Current Signal Transduction Therapy
Volume: 1 Issue: 1 Year: 2006 Page: 13-23
Author(s): Ian Collins, Paul Workman

Combinatorial Chemistry and Fragment Screening - Two Unlike Siblings?

Journal: Current Drug Discovery Technologies
Volume: 2 Issue: 1 Year: 2005 Page: 1-12
Author(s): Hans Peter Nestler

Library Design for Fragment Based Screening

Journal: Current Topics in Medicinal Chemistry
Volume: 5 Issue: 8 Year: 2005 Page: 751-762
Author(s): Ansgar Schuffenhauer, Simon Ruedisser, Andreas Marzinzik, Wolfgang Jahnke, Paul Selzer, Edgar Jacoby

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