Search Result "hit-rates"

G Protein-Coupled Receptors: Target-Based In Silico Screening

Journal: Current Pharmaceutical Design
Volume: 15 Issue: 3 Year: 2009 Page: 4049-4068
Author(s): Hanoch Senderowitz, Yael Marantz

Synergies of Virtual Screening Approaches

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 8 Issue: 9 Year: 2008 Page: 927-933
Author(s): Ingo Muegge

ADME Optimization and Toxicity Assessment in Early- and Late-Phase Drug Discovery

Journal: Current Topics in Medicinal Chemistry
Volume: 9 Issue: 1 Year: 2009 Page: 965-980
Author(s): Gary W. Caldwell, Zhengyin Yan, Weimin Tang, Malini Dasgupta, Becki Hasting

Fragment-Based Drug Discovery and Molecular Docking in Drug Design

Journal: Current Pharmaceutical Biotechnology
Volume: 16 Issue: 1 Year: 2015 Page: 11-25
Author(s): Tao Wang,Mian-Bin Wu,Zheng-Jie Chen,Hua Chen,Jian-Ping Lin,Li-Rong Yang

Rational Drug Design: The Search for Ras Protein Hydrolysis Intermediate Conformation Inhibitors with Both Affinity and Specificity

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 12 Year: 2013 Page: 2246-2258
Author(s): Xiliang Zheng,Zuojia Liu,Dan Li,Erkang Wang,Jin Wang

A Simple Method for Analyzing Actives in Random RNAi Screens: Introducing the “H Score” for Hit Nomination & Gene Prioritization

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 15 Issue: 9 Year: 2012 Page: 686-704
Author(s): Bhavneet Bhinder,Hakim Djaballah

The Design of Screening Libraries Targeted at G-Protein Coupled Receptors

Journal: Current Topics in Medicinal Chemistry
Volume: 4 Issue: 6 Year: 2004 Page: 581-589
Author(s): Roger Crossley

Selection, Application, and Validation of a Set of Molecular Descriptors for Nuclear Receptor Ligands

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 7 Issue: 5 Year: 2004 Page: 407-412
Author(s): Eugene L. Stewart, Peter J. Brown, James A. Bentley, Timothy M. Willson

Comparison of Methods for Sequential Screening of Large Compound Sets

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 9 Issue: 2 Year: 2006 Page: 115-122
Author(s): Paul E. Blower, Kevin P. Cross, Gabriel S. Eichler, Glenn J. Myatt, John N. Weinstein, Chihae Yang

Recent Developments in Focused Library Design: Targeting Gene-Families

Journal: Current Topics in Medicinal Chemistry
Volume: 6 Issue: 1 Year: 2006 Page: 19-29
Author(s): Jennifer L. Miller

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