Search Result "Tissue/plasma partition coefficients"

Research Article

Prediction of Tissue to Plasma Concentration Ratios of Drugs in the Rat from Experimentally Estimated Volume of Distribution: Application of Allometry

Journal: Current Drug Metabolism
Volume: 19 Issue: 2 Year: 2018 Page: 155-164
Author(s): Iftekhar Mahmood

Do We Need to Optimize Plasma Protein and Tissue Binding in Drug Discovery?

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 450-466
Author(s): Xingrong Liu, Cuiping Chen, Cornelis E.C.A. Hop

Liposaccharides for Improved Oral Delivery of Tobramycin

Journal: Drug Delivery Letters
Volume: 2 Issue: 2 Year: 2012 Page: 92-97
Author(s): Adel S. Abdelrahim, Pavla Simerska, Istvan Toth

Insight into Tissue Unbound Concentration: Utility in Drug Discovery and Development

Journal: Current Drug Metabolism
Volume: 14 Issue: 3 Year: 2013 Page: 324-340
Author(s): T. Thanga Mariappan,Sandhya Mandlekar,Punit Marathe

Prediction of Distribution of Neutral, Acidic and Basic Structurally Diverse Compounds Between Blood and Brain by the Nonlinear Methodology

Journal: Medicinal Chemistry
Volume: 4 Issue: 2 Year: 2008 Page: 170-189
Author(s): Huabei Zhang, Shaoping Hu, Yaling Zhang

Comparative Efflux of Saquinavir, Ritonavir and Lopinavir from Primary Human Cells

Journal: Drug Metabolism Letters
Volume: 4 Issue: 4 Year: 2010 Page: 241-245
Author(s): Bilge Diker, Omar Janneh, Rolf P.G. van Heeswijk, Karen F.T. Copeland

The Use of Immobilised Artificial Membrane (IAM) Chromatography for Determination of Lipophilicity

Journal: Current Computer-Aided Drug Design
Volume: 2 Issue: 4 Year: 2006 Page: 341-352
Author(s): Francesco Barbato

Review Article

Current State and Future Perspectives in QSAR Models to Predict Blood- Brain Barrier Penetration in Central Nervous System Drug R&D

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 17 Issue: 3 Year: 2017 Page: 247-257
Author(s): Juan F. Morales,Sebastian Scioli Montoto,Pietro Fagiolino,Maria E. Ruiz

Synthesis, Physicochemical Properties and In Vitro Permeation Studies of New Ketorolac Ester Derivatives

Journal: Current Drug Delivery
Volume: 4 Issue: 3 Year: 2007 Page: 205-210
Author(s): Carmelo Puglia, Rosanna Filosa, Antonella Peduto, Paolo de Caprariis, Gianpiero Boatto, Maria Nieddu, Natale Alfredo Santagati, Francesco Bonina

High Throughput Screening of Physicochemical Properties and In Vitro ADME Profiling in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 12 Issue: 3 Year: 2009 Page: 315-329
Author(s): Hong Wan, Anders G. Holmen

Previous   Next

Go To   Results 1 - 1 of 626

Apply Filters

Volume Years
Article Type
Publication Title
Subject Title

Content Type


© 2025 Bentham Science Publishers | Privacy Policy