Search Result "Time dependent inhibition"

Higher Throughput Human Hepatocyte Assays for the Evaluation of Time-Dependent Inhibition of CYP3A4

Journal: Drug Metabolism Letters
Volume: 5 Issue: 3 Year: 2011 Page: 183-191
Author(s): Albert P. Li, Utkarsh Doshi

Research Article

Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme

Journal: Drug Metabolism Letters
Volume: 10 Issue: 4 Year: 2016 Page: 270-277
Author(s): Jayalakshmi Sridhar,Jiawang Liu,Rajesh Komati,Richard Schroeder,Quan Jiang,Phan Tram,Kevin Riley,Maryam Foroozesh

An Examination of IC50 and IC50-Shift Experiments in Assessing Time-Dependent Inhibition of CYP3A4, CYP2D6 and CYP2C9 in Human Liver Microsomes

Journal: Drug Metabolism Letters
Volume: 2 Issue: 1 Year: 2008 Page: 51-59
Author(s): Loren M. Berry, Zhiyang Zhao

Impact of Time-Dependent Inactivation on the Estimation of Enzyme Kinetic Parameters for Midazolam

Journal: Drug Metabolism Letters
Volume: 3 Issue: 1 Year: 2009 Page: 45-53
Author(s): Craig Giragossian, Jennifer LaPerle, Rachel E. Kosa, Sarah Gillian

Evaluation of Different Approaches to Identifying a Higher Throughput Assay for Time-Dependent Inhibition (TDI)

Journal: Drug Metabolism Letters
Volume: 5 Issue: 2 Year: 2011 Page: 104-113
Author(s): M. Kajbaf, R. Longhi, S. Fontana

Cyclin-Dependent Kinase Inhibition by Flavoalkaloids

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 12 Issue: 7 Year: 2012 Page: 632-649
Author(s): S. K. Jain,S. B. Bharate,R. A. Vishwakarma

Presynaptic Cell Dependent Modulation of Inhibition in Cortical Regions

Journal: Current Neuropharmacology
Volume: 7 Issue: 2 Year: 2009 Page: 125-131
Author(s): Afia B. Ali

Evaluation of Time-Dependent Cytochrome P450 Inhibition in a High-Throughput, Automated Assay: Introducing a Novel Area Under the Curve Shift Approach

Journal: Drug Metabolism Letters
Volume: 6 Issue: 1 Year: 2012 Page: 43-53
Author(s): Sophie Mukadam, Suzanne Tay, Daniel Tran, Leslie Wang, Erlie M. Delarosa, S. Cyrus Khojasteh, Jason S. Halladay, Jane R. Kenny

In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities

Journal: Drug Metabolism Letters
Volume: 9 Issue: 1 Year: 2015 Page: 48-62
Author(s): Charles Awortwe,Vamshi K. Manda,Cristina Avonto,Shabana I. Khan,Ikhlas A. Khan,Larry A. Walker,Patrick J. Bouic,Bernd Rosenkranz

Ligustrazine Suppresses the Growth of HRPC Cells through the Inhibition of Cap- Dependent Translation Via Both the mTOR and the MEK/ERK Pathways

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 15 Issue: 6 Year: 2015 Page: 764-772
Author(s): Jiaoyan Han,Jiao Song,Xiangyun Li,Ming Zhu,Wei Guo,Wei Xing,Rongshen Zhao,Xiao He,Xiaoping Liu,Shali Wang,Yunyun Li,Hong Huang,Xiang Xu

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