Search Result "DFG in/out"

Insight into the Binding of DFG-out Allosteric Inhibitors to B-Raf Kinase Using Molecular Dynamics and Free Energy Calculations

Journal: Current Computer-Aided Drug Design
Volume: 11 Issue: 2 Year: 2015 Page: 124-136
Author(s): Luis Coronel,Jose M. Granadino-Roldán,Marta Pinto,Maria S. Tomas,Maria D. Pujol,Jaime Rubio-Martinez

Review Article

Current Insights into the Role of BRAF Inhibitors in Treatment of Melanoma

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 23 Issue: 3 Year: 2023 Page: 278-297
Author(s): Ankit Kumar Singh

Design, Synthesis and Antitumor Activities of Bis-arylureas and Bis-arylamides Based on1H-benzo[d]imidazole Moiety as Novel BRafV600E/VEGFR2 Dual inhibitors

Journal: Letters in Drug Design & Discovery
Volume: 11 Issue: 9 Year: 2014 Page: 1079-1089
Author(s): Weimin Yang,Yadong Chen,Yanmin Zhang,Sanzhi Tang,Hongli Chen,Weifang Tang,Tao Lu

Diaryl Urea: A Privileged Structure in Anticancer Agents

Journal: Current Medicinal Chemistry
Volume: 23 Issue: 15 Year: 2016 Page: 1528-1548
Author(s): Laura Garuti,Marinella Roberti,Giovanni Bottegoni,Mariarosaria Ferraro

Non-ATP Competitive Protein Kinase Inhibitors

Journal: Current Medicinal Chemistry
Volume: 17 Issue: 2 Year: 2010 Page: 2804-2821
Author(s): L. Garuti, M. Roberti, G. Bottegoni

Selectivity Filters to Edit Out Deleterious Side Effects in Kinase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 7 Year: 2011 Page: 788-799
Author(s): Sean Sessel, Ariel Fernandez

Research Article

Homology Modelling, Docking-based Virtual Screening, ADME Properties, and Molecular Dynamics Simulation for Identification of Probable Type II Inhibitors of AXL Kinase

Journal: Letters in Drug Design & Discovery
Volume: 19 Issue: 3 Year: 2022 Page: 214-241
Author(s): Heena R. Bhojwani,Urmila J. Joshi

Research Article

Design, Synthesis and Biological Evaluation of Uracil Derivatives as Novel VEGFR-2 Inhibitors

Journal: Current Pharmaceutical Design
Volume: 24 Issue: 6 Year: 2018 Page: 734-740
Author(s): Jingwei Liang,Xinyang Li,Su Yang,Xin He,Mingyang Wang,Fanhao Meng

Discovery of Small Molecule c-Met Inhibitors: Evolution and Profiles of Clinical Candidates

Journal: Anti-Cancer Agents in Medicinal Chemistry
Volume: 10 Issue: 1 Year: 2010 Page: 7-27
Author(s): Ted L. Underiner, Torsten Herbertz, Sheila J. Miknyoczki

Rational Approaches Towards Lead Optimization of Kinase Inhibitors: The Issue of Specificity

Journal: Current Pharmaceutical Design
Volume: 19 Issue: 26 Year: 2013 Page: 4714-4738
Author(s): Preethi Badrinarayan,G. Narahari Sastry

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