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BACE1 Deficient Mice: Their Role in Drug Target Validation and Implications for Alzheimers Disease Therapies

Journal: Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents
Volume: 3 Issue: 1 Year: 2003 Page: 47-55
Author(s): Robert Vassar

Alzheimer’s Disease: Treatment of Multi-Factorial Disorders with Multi-Target Approach

Journal: Mini-Reviews in Medicinal Chemistry
Volume: 23 Issue: 4 Year: 2023 Page: 380-398
Author(s):

γ-Secretase, Apolipoprotein E and Cellular Cholesterol Metabolism

Journal: Current Alzheimer Research
Volume: 9 Issue: 2 Year: 2012 Page: 189-199
Author(s): Jochen Walter

Journal: Current Enzyme Inhibition
Volume: 9 Issue: 1 Year: 2013 Page: 3-14
Author(s): Christopher J. Holler, Michael P. Murphy

RCAN1 Increases Aβ Generation by Promoting N-glycosylation via Oligosaccharyltransferase

Journal: Current Alzheimer Research
Volume: 11 Issue: 4 Year: 2014 Page: 332-339
Author(s): Tan Wang, Heng Liu, Yun Wang, Changqing Liu, Xiulian Sun

The Normal and Pathologic Roles of the Alzheimer's β -secretase, BACE1

Journal: Current Alzheimer Research
Volume: 11 Issue: 5 Year: 2014 Page: 441-449
Author(s): Patty C. Kandalepas, Robert Vassar

There is no Failure, Only Discovery—the Year Ahead for CARving New Paths

Journal: Current Alzheimer Research
Volume: 17 Issue: 1 Year: 2020 Page: 1-2
Author(s): Debomoy K. Lahiri

BACE1 Structure and Function in Health and Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 100-120
Author(s): Sarah L. Cole, Roger Vassar

Progress in the Discovery of BACE Inhibitors

Journal: Current Pharmaceutical Design
Volume: 11 Issue: 2 Year: 2005 Page: 3383-3404
Author(s): L. A. Thompson, J. J. Bronson, F. C. Zusi

The Basic Biology of BACE1: A Key Therapeutic Target for Alzheimers Disease

Journal: Current Genomics
Volume: 8 Issue: 8 Year: 2007 Page: 509-530
Author(s): R. Vassar, S. L. Cole