Search Result "the half-life for clearance"

General Review Article

Recent Advances in Half-life Extension Strategies for Therapeutic Peptides and Proteins

Journal: Current Pharmaceutical Design
Volume: 24 Issue: 41 Year: 2018 Page: 4932-4946
Author(s): Huanbo Tan,Wencheng Su,Wenyu Zhang,Pengju Wang,Michael Sattler,Peijian Zou

Review Article

Optimization of Protein and Peptide Drugs Based on the Mechanisms of Kidney Clearance

Journal: Protein & Peptide Letters
Volume: 25 Issue: 6 Year: 2018 Page: 514-521
Author(s): Huizi Wu,Jiaguo Huang

Review Article

New Directions for Half-Life Extension of Protein Therapeutics: The Rise of Antibody Fc Domains and Fragments

Journal: Current Pharmaceutical Biotechnology
Volume: 17 Issue: 15 Year: 2016 Page: 1348-1352
Author(s): Lili Wang,Tianlei Ying

Predicting Clearance in Humans from In Vitro Data

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 4 Year: 2011 Page: 334-339
Author(s): R. Scott Obach

Research Article

Higher Anti-angiogenesis Activity, Better Cellular Uptake and Longer Half-life of a Novel Glyco-modified Endostatin by Polysulfated Heparin

Journal: Current Pharmaceutical Biotechnology
Volume: 19 Issue: 12 Year: 2018 Page: 996-1004
Author(s): Feng Sun,Abdul Sami Shaikh,Juan Wang,Hui Gao,Zhifang Yang,Zhendong Wang,Yan Li,Fengshan Wang,Haining Tan

ARC - Augmented Renal Clearance

Journal: Current Pharmaceutical Biotechnology
Volume: 12 Issue: 1 Year: 2011 Page: 2020-2029
Author(s): Andrew A. Udy, Michael T. Putt, Robert J. Boots, Jeffrey Lipman

Application of Simple Mathematical Expressions to Relate Half-Lives of Drugs in Mice to Those in Humans

Journal: Drug Metabolism Letters
Volume: 1 Issue: 2 Year: 2007 Page: 127-129
Author(s): Kenneth Bachmann, Jonathan Chupka, Paul Erhardt, Donald White

Granulocyte Apoptosis and Macrophage Clearance of Apoptotic Cells as Targets for Pharmacological Intervention in Inflammatory Diseases

Journal: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Volume: 5 Issue: 1 Year: 2006 Page: 3-12
Author(s): Nicola A. Riley, Carol Ward, Deborah A. Sawatzky, Tara A. Sheldrake, Ian Dransfield, Christopher Haslett, Adriano G. Rossi

Scaling In Vivo Pharmacokinetics from In Vitro Metabolic Stability Data in Drug Discovery

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 2 Year: 2010 Page: 159-169
Author(s): Wendy Klopf, Philip Worboys

Systematic and Pairwise Analysis of the Effects of Aromatic Halogenation and Trifluoromethyl Substitution on Human Liver Microsomal Clearance

Journal: Drug Metabolism Letters
Volume: 5 Issue: 4 Year: 2011 Page: 232-242
Author(s): Hao Sun, Christopher E. Keefer, Dennis O. Scott

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