Search Result "S9."

Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability

Journal: Drug Metabolism Letters
Volume: 10 Issue: 2 Year: 2016 Page: 83-90
Author(s): Samantha J. Richardson, April Bai, Ashutosh A. Kulkarni, Mehran F. Moghaddam

Research Article

Quantification of Sulfotransferases 1A1 and 1A3/4 in Tissue Fractions and Cell Lines by Multiple Reaction Monitoring Mass Spectrometry

Journal: Drug Metabolism Letters
Volume: 11 Issue: 1 Year: 2017 Page: 35-47
Author(s): Sho Yoshitake,Melissa McKay-Daily,Masaki Tanaka,Zeqi Huang

Gender Specific Drug Metabolism of PF-02341066 in Rats — Role of Sulfoconjugation

Journal: Current Drug Metabolism
Volume: 11 Issue: 4 Year: 2010 Page: 296-306
Author(s): Wei-Zhu Zhong, Jenny Zhan, Ping Kang, Shinji Yamazaki

Letter Article

Genotoxicity of 4-(piperazin-1-yl)-8-(trifluoromethyl)pyrido[2,3-e][1,2,4] triazolo[4,3-a]pyrazine, a Potent H4 Receptor Antagonist for the Treatment of Allergy: Evidence of Glyoxal Intermediate Involvement

Journal: Drug Metabolism Letters
Volume: 11 Issue: 2 Year: 2017 Page: 144-148
Author(s): Mithat Gunduz,Amanda L. Cirello,Peter Klimko,Jennifer L. Dumouchel,Upendra A. Argikar

Research Article

Preliminary Studies on Ligand-based Design and Evaluation of New Mycobacterial ATP Synthase Inhibitors

Journal: Current Drug Therapy
Volume: 13 Issue: 1 Year: 2018 Page: 56-73
Author(s): Satheeshkumar Sellamuthu,Amer H. Asseri,Hojjat Ghasemi Goojani,Gopal Nath,Sushil K. Singh

The Prediction of the Hepatic Clearance of Tanshinone IIA in Rat Liver Subcellular Fractions: Accuracy Improvement

Journal: Current Drug Metabolism
Volume: 9 Issue: 1 Year: 2008 Page: 39-45
Author(s): Guang-Ji Wang, Peng Li, Jing Li, Qian Zhang, Xin Liu, Alexander Khlentzos, Michael S. Roberts

Cigarette Smoking, Metabolic Activation and Carcinogenesis

Journal: Current Drug Metabolism
Volume: 5 Issue: 5 Year: 2004 Page: 363-373
Author(s): Akiyoshi Nishikawa, Yukio Mori, In-Seon Lee, Takuji Tanaka, Masao Hirose

Identification of a Novel Intestinal First Pass Metabolic Pathway: NQO1 Mediated Quinone Reduction and Subsequent Glucuronidation

Journal: Current Drug Metabolism
Volume: 8 Issue: 2 Year: 2007 Page: 137-149
Author(s): Haiping Hao, Guangji Wang, Nan Cui, Jing Li, Lin Xie, Zuoqi Ding

Research Article

The Role of Aldehyde Oxidase in the Metabolic Clearance of Substituted Benzothiazoles

Journal: Drug Metabolism Letters
Volume: 14 Issue: 2 Year: 2021 Page: 126-136
Author(s): Yohannes Teffera,Jingzhou Liu,Paul Krolikowski,Zhiyang Zhao

Research Article

Investigation of Ocular Bioactivation Potential and the Role of Cytochrome P450 2D Enzymes in Rat

Journal: Drug Metabolism Letters
Volume: 11 Issue: 2 Year: 2017 Page: 102-110
Author(s): Jennifer L. Dumouchel,Upendra A. Argikar,Jaimie Spear,Ann Brown,Christine E. Dunne,Valerie M. Kramlinger,Amanda L. Cirello,Mithat Gunduz

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