Search Result "M2000"

Research Article

The Inhibitory Role of M2000 (β-D-Mannuronic Acid) on Expression of Toll-like Receptor 2 and 4 in HT29 Cell Line

Journal: Recent Patents on Inflammation & Allergy Drug Discovery
Volume: 13 Issue: 1 Year: 2019 Page: 57-65
Author(s): Laleh Sharifi,Mona Moshiri,Mohammad M.S. Dallal,Mohammad H. Asgardoon,Maryam Nourizadeh,Saied Bokaie,Abbas Mirshafiey

Research Article

Modification of Sexual Hormones in Rheumatoid Arthritis Patients by M2000 (β-D-mannuronic Acid) as a Novel NSAID with Immunosuppressive Property

Journal: Endocrine, Metabolic & Immune Disorders - Drug Targets
Volume: 18 Issue: 5 Year: 2018 Page: 530-536
Author(s): Mozhgan Jahanbakhshi,Zohreh Babaloo,Seyed Shahabeddin Mortazavi-Jahromi,Maryam Monsef Shokri,Hossein Ahmadi,Abbas Mirshafiey

M2000, Foundation of a New Generation Among NSAIDs

Journal: Letters in Drug Design & Discovery
Volume: 2 Issue: 5 Year: 2005 Page: 412-423
Author(s): A. Mirshafiey, B. Rehm, S. Cuzzocrea, H. Matsuo, E. Mazzon, S. Nakane, C- S. Koh, S. Miyoshi

Clinical Trial

The Anti-Migraine Effects of M2000 (β-D-Mannuronic Acid) on a Patient with Rheumatoid Arthritis: Case Report

Journal: Current Clinical Pharmacology
Volume: 12 Issue: 2 Year: 2017 Page: 127-130
Author(s): Mahdi Vojdanian,Hossein Ahmadi,Ahmad Reza Jamshidi,Mahdi Mahmoudi,Farhad Gharibdoost,Anis Barati,Abbas Mirshafiey

Research Article

The Potent Inhibitory Effect of β-D-Mannuronic Acid (M2000) as a Novel NSAID with Immunosuppressive Property on Anti-Cyclic Citrullinated Peptide Antibodies, Rheumatoid Factor and Anti-dsDNA Antibodies in Patients with Rheumatoid Arthritis

Journal: Current Drug Discovery Technologies
Volume: 14 Issue: 3 Year: 2017 Page: 206-214
Author(s): Hossein Ahmadi,Ahmad R. Jamshidi,Mahdi Mahmoudi,Salvatore Cuzzocrea,Mohammad Javad Fattahi,Anis Barati,Bernd H. A. Rehm,Hidenori Matsuo,Abbas Mirshafiey

Review Article

β-D-Mannuronic Acid (M2000) as a Landmark in Pharmacology

Journal: Current Drug Discovery Technologies
Volume: 18 Issue: 1 Year: 2021 Page: 47-57
Author(s): Nada A.G. Gaafar,Alireza Razavi,Abbas Mirshafiey

Research Article

The Oral Administration Effect of Drug Mannuronic Acid (M2000) on Gene Expression of Matrix and Tissue Inhibitor of Metalloproteinases in Rheumatoid Arthritis Patients

Journal: Current Drug Discovery Technologies
Volume: 17 Issue: 5 Year: 2020 Page: 704-710
Author(s): Nada A.G. Gaafar,Mona Aslani,Zahra Aghazadeh,Alireza Razavi,Abbas Mirshafiey

Research Article

Efficacy of β-D-Mannuronic Acid [M2000] on the Pro-Apoptotic Process and Inflammatory-Related Molecules NFκB, IL-8 and Cd49d using Healthy Donor PBMC

Journal: Current Drug Discovery Technologies
Volume: 17 Issue: 2 Year: 2020 Page: 225-232
Author(s): Atousa Khalatbari,Mehdi Mahdavi,Fahimeh Jafarnezhad,Sanaz Afraei,Farzaneh Tofighi Zavareh,Zahra Aghazadeh,Afshin Ghaderi,Abbas Mirshafiey

Research Article

The Safety Property of β-D-Mannuronic Acid (M2000) as a Novel Immunosuppressive Agent on Differentiation, Maturation and Function of Human Dendritic Cells

Journal: Current Drug Discovery Technologies
Volume: 13 Issue: 3 Year: 2016 Page: 164-169
Author(s): Nazanin A. Fard,Nakisa Tabrizian,Reza Mirzaei,Nasrin Motamed,Farzaneh T. Zavareh,Abbas Mirshafiey

Research Article

The Biology of β-D-mannuronic acid (M2000) on Human Dendritic Cell Based on MicroRNA-155 and MicroRNA-221

Journal: Current Drug Discovery Technologies
Volume: 14 Issue: 1 Year: 2017 Page: 53-58
Author(s): Nakisa Tabrizian,Nazanin Arjomand Fard,Ali Farazmand,Rahil Eftekhari,Farzaneh Tofighi Zavareh,Abbas Mirshafiey

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