Search Result "γ-secretase substrates"

Research Article

Identification of High-affinity Small Molecules Targeting Gamma Secretase for the Treatment of Alzheimer’s Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 19 Issue: 13 Year: 2019 Page: 1173-1187
Author(s): Meer Asif Ali,Sugunakar Vuree,Himshikha Goud,Tajamul Hussain,Anuraj Nayarisseri,Sanjeev Kumar Singh

Review of Synthesis, Assay, and Prediction of β and γ-secretase Inhibitors

Journal: Current Topics in Medicinal Chemistry
Volume: 12 Issue: 8 Year: 2012 Page: 828-844
Author(s): Helena Nino,Jose Enrique Rodriguez-Borges,Xerardo Garcia-Mera,Francisco Prado-Prado

Review Article

Gamma Secretase as an Important Drug Target for Management ofAlzheimer’s Disease: A Comprehensive Review

Journal: Current Topics in Medicinal Chemistry
Volume: 24 Issue: 2 Year: 2024 Page: 109-127
Author(s):

Gamma-Secretase as a Pharmacological Target in Alzheimer Disease Research: When, Why and How?

Journal: Current Pharmaceutical Design
Volume: 12 Issue: 3 Year: 2006 Page: 4313-4335
Author(s): Chewki Ziani-Cherif, Bachir Mostefa-Kara, Fatima Z. Brixi-Gormat

γ-Secretase Substrates and their Implications for Drug Development in Alzheimers Disease

Journal: Current Topics in Medicinal Chemistry
Volume: 11 Issue: 1 Year: 2011 Page: 1513-1527
Author(s): Alberto Lleo, Carlos A. Saura

Probing Proteinase Active Sites Using Oriented Peptide Mixture Libraries - ADAM-10

Journal: Letters in Drug Design & Discovery
Volume: 1 Issue: 1 Year: 2004 Page: 6-13
Author(s): John L. Krstenansky, Jihong Wang, Gregg R. Chenail, Matthew R. Tiffany, Geoffrey M. Kuesters, Barbara C. Natke, John J. Nestor, Jr.

Fluorescent Substrates Useful as High Throughput Screening Tools for ADAM9

Journal: Combinatorial Chemistry & High Throughput Screening
Volume: 13 Issue: 4 Year: 2010 Page: 358-365
Author(s): Marcia L. Moss, Fred H. Rasmussen, Raphael Nudelman, Peter J. Dempsey, Jason Williams

Role of the APP Non-Amyloidogenic Signaling Pathway and Targeting α-Secretase as an Alternative Drug Target for Treatment of Alzheimers Disease

Journal: Current Medicinal Chemistry
Volume: 14 Issue: 2 Year: 2007 Page: 2848-2864
Author(s): S. Bandyopadhyay, L. E. Goldstein, D. K. Lahiri, J. T. Rogers

Presenilin and γ -Secretase Activity: A Viable Therapeutic Target for Alzheimers Disease?

Journal: Current Signal Transduction Therapy
Volume: 5 Issue: 2 Year: 2010 Page: 128-140
Author(s): Run Yan, Justin V. McCarthy

γ-Secretase Inhibition and Modulation for Alzheimers Disease

Journal: Current Alzheimer Research
Volume: 5 Issue: 2 Year: 2008 Page: 158-164
Author(s): Michael S. Wolfe

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