Treatment of Recurrent Epistaxis in HHT

Title: Treatment of Recurrent Epistaxis in HHT

Volume: 12 Issue: 10

Author(s): U. W. Geisthoff, M. L. Fiorella and R. Fiorella

Affiliation:

Keywords: Rendu-Osler-Weber disease, hereditary haemorrhagic telangiectasia, laser therapy, septodermoplasty, review

Abstract: No optimal treatment modality is currently available for the treatment of recurrent epistaxis in HHT. In this review, different therapeutic concepts are discussed together with their pathophysiologic background. Patients often profess a preventive effect for nasal ointments and use packings which can be self-administed in the case of bleeding. An effective first-line treatment for physicians is the endonasal laser coagulation or argon plasma coagulation. A second line surgical procedure is septodermoplasty according to Saunders which can provide long-lasting relief if performed correctly. There have been reports on antifibrinolytic agents and hormones, but their efficacy has yet to be determined.

Cite this article as:

Geisthoff W. U., Fiorella L. M. and Fiorella R., Treatment of Recurrent Epistaxis in HHT, Current Pharmaceutical Design 2006; 12 (10) . https://dx.doi.org/10.2174/138161206776361255