Biological Applications of Hammerhead Ribozymes as Anti-viral Molecules

Brooke      Lustig; Kuan-Teh      Jeang

doi:10.2174/0929867013372373

Abstract

Ribozymes are catalytic RNAs that can cleave substrate RNAs in a sequence specific manner. Here we survey, in brief, the structure of hammerhead and hairpin ribozymes and discuss their applications as molecular antiviral molecules for HIV-1.

Keywords: Hammerhead Ribozymes, Anti-viral Molecules, RIBOZYMES, HAMMERHEAD RIBOZYME

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Current Medicinal Chemistry

Title: Biological Applications of Hammerhead Ribozymes as Anti-viral Molecules

Volume: 8 Issue: 10

Author(s): Brooke Lustig and Kuan-Teh Jeang

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Keywords: Hammerhead Ribozymes, Anti-viral Molecules, RIBOZYMES, HAMMERHEAD RIBOZYME

Abstract: Ribozymes are catalytic RNAs that can cleave substrate RNAs in a sequence specific manner. Here we survey, in brief, the structure of hammerhead and hairpin ribozymes and discuss their applications as molecular antiviral molecules for HIV-1.

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Lustig Brooke and Jeang Kuan-Teh, Biological Applications of Hammerhead Ribozymes as Anti-viral Molecules, Current Medicinal Chemistry 2001; 8 (10) . https://dx.doi.org/10.2174/0929867013372373