Regenerative Dentistry and Stem Cells: A Multilineage Differentiation as a Safe and Useful Alternative Way of Harvesting and Selection Adipose Derived Mesenchymal Stem Cells

Title:Regenerative Dentistry and Stem Cells: A Multilineage Differentiation as a Safe and Useful Alternative Way of Harvesting and Selection Adipose Derived Mesenchymal Stem Cells

Volume: 19 Issue: 16

Author(s): Dorina Lauritano*, Palmieri Annalisa, Candotto Valentina and Carinci Francesco

Affiliation:

• University of Milan-Bicocca, via Cadore 48, 20900 Monza (MB),Italy

Keywords: Adipose derived stem cells, dentistry, biostimulation, fibroblasts, micrograft, stem niches.

Abstract: Background: This review aims to address procedures and indications for the application of the adipose-derived stem cells (ADSCs) for regenerative dentistry. ADSCs have rarely been used in this particular field; conversely, experience from other clinical fields and basic research seems to recommend the suitability of this application.

Aims and Methods: We reviewed 32 out of 193 articles on Medline sorted by the relevance option. The main purpose of this paper is to perform a short review of the application of stem cells in regenerative dentistry, describing a multilineage differentiation as a safe and useful alternative way of harvesting and selection of ADSCs.

Results and Conclusion: The most common derivation of stem cells for regenerative dentistry is from the adipose tissue. There are conditions in which the levy adipose cannot be easily achieved, or where large amount of grafting is not needed. For this purpose, the possibility of selecting stromal stem cells directly from the lax subcutaneous connective tissue, preferably of the head region, would allow a technical simplification.

Cite this article as:

Lauritano Dorina *, Annalisa Palmieri , Valentina Candotto and Francesco Carinci , Regenerative Dentistry and Stem Cells: A Multilineage Differentiation as a Safe and Useful Alternative Way of Harvesting and Selection Adipose Derived Mesenchymal Stem Cells, Current Drug Targets 2018; 19 (16) . https://dx.doi.org/10.2174/1389450119666180816122230