Heterocyclic Compounds as Inflammation Inhibitors

Title: Heterocyclic Compounds as Inflammation Inhibitors

Volume: 9 Issue: 10

Author(s): Sham M. Sondhi, Nidhi Singhl, Monika Johar, B.S. Narayan Reddy and J. William Lown

Affiliation:

Keywords: Heterocyclic compounds, Inflammation inhibitors, nonsteroidal

Abstract: Clinical use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with significant toxicity particularly in the gastrointestinal tract and kidney. Various approaches such as formulation & co-administration (of agents to protect the stomach), chemical manipulation and synthesis of new safer anti-inflammatory drugs reported in the literature to overcome the toxicity of NSAIDs have been summarized. As far as synthesis of new more effective and safer anti-inflammatory drugs is concerned, we have reported recent findings in the area of synthesis of heterocyclic compounds such as pyrimidines, imidazole, benzimidazole, thiazole, thiazolidine, acridine, thiourea, alkanoic acid derivatives and other related heterocyclic compounds and their role as inflammation inhibitors.

Cite this article as:

Sondhi M. Sham, Singhl Nidhi, Johar Monika, Reddy Narayan B.S. and Lown William J., Heterocyclic Compounds as Inflammation Inhibitors, Current Medicinal Chemistry 2002; 9 (10) . https://dx.doi.org/10.2174/0929867024606678