Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists

Title: Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists

Volume: 5 Issue: 3

Author(s): Brad O. Buckman, Ameen Ghannam, Angela Li, Meina Liang, Raju Mohan and Howard P. Ng

Affiliation:

Keywords: solid-phase synthesis, ccri receptor antagonist

Abstract: An automated, parallel, solid-phase synthesis and screening strategy using commercially available aryl acetic acids as starting materials has discovered novel, non-peptide CCR1 antagonists (Ki < 100 nM).

Cite this article as:

Buckman O. Brad, Ghannam Ameen, Li Angela, Liang Meina, Mohan Raju and Ng P. Howard, Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists, Combinatorial Chemistry & High Throughput Screening 2002; 5 (3) . https://dx.doi.org/10.2174/1386207024607284