氧化石墨烯作为干细胞支架：概述

Title:Graphene Oxide as Scaffolds for Stem Cells: An Overview

Volume: 17 Issue: 9

关键词: 干细胞，氧化石墨烯，脂肪组织衍生的间充质基质/干细胞，地形图，分化，组织工程

摘要: Graphene and graphene oxide topography have an effect on the fate of stem cells such as adhesion, differentiation, and proliferation. This overview clearly shows that a new design and manipulation of associated graphene oxide stem cell culture platforms are of paramount importance as a focus in stem cell to tissue engineering applications. This overview also proposes that a film of graphene oxide is an efficient platform to modulate structure and function of multipotent mesenchymal stem/stromal cells (MSCs) and in special human adipose tissue derived mesenchymal stromal/stem cells (AT-MSCs). The implication of graphene oxide on osteogenesis, neurogenesis, oligodendrogenesis, adipogenic and epithelial differentiation is also discussed. Graphene oxide toxicity on stem cells and the importance of GO application on ATMSCs differentiation and proliferation are final topics that are being discussed.

Cite this article as:

Graphene Oxide as Scaffolds for Stem Cells: An Overview, Current Molecular Medicine 2017; 17 (9) . https://dx.doi.org/10.2174/1566524018666180308111915