New Strategies for the Prevention and Treatment of Bone Loss - From Mechanical Loading Point of View

Title:New Strategies for the Prevention and Treatment of Bone Loss - From Mechanical Loading Point of View

Volume: 23 Issue: 41

Author(s): Ce Shi , Bai Yang*Hongchen Sun*

Affiliation:

• State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun, 130021,China

• Department of Oral Pathology, School and Hospital of Stomatology, Jilin University, Changchun, 130021,China

Keywords: Mechanical loading, bone, bone mass, bone density, osteocytes, osteoblasts, bone loss.

Abstract: In contemporary society, a large number of adults experience more or less decrease in bone mass or bone density. It is known that bone, in response to mechanical loading, undergoes continuous remodeling throughout life, which helps in the growth and maintenance of the skeleton. Since mechanical loading acts as an important stimulus for bone growth and maintenance, it can be used as a strategy to prevent and treat the conditions of bone loss. This review summarizes the current knowledge about the effects of mechanical loading on bone, in the level of cells and tissue.

Cite this article as:

Shi Ce , Yang Bai *, Sun Hongchen *, New Strategies for the Prevention and Treatment of Bone Loss - From Mechanical Loading Point of View, Current Pharmaceutical Design 2017; 23 (41) . https://dx.doi.org/10.2174/1381612823666171108121350