Tetraacyldiborates: Selective and Efficient Acylation Reagents Suitable for Multiple Parallel Synthetic Applications

Title: Tetraacyldiborates: Selective and Efficient Acylation Reagents Suitable for Multiple Parallel Synthetic Applications

Volume: 6 Issue: 2

Author(s): Elmer J. Gentry, Hanumaiah Telikepalli, Pusuluri Srinivas and Lester A. Mitscher

Affiliation:

Keywords: Tetraacyldiborates, Acylation Reagents, Boron-based, anhydrides, chelation

Abstract: Boron-based mixed anhydrides are rapidly reactive, easy to prepare, cheap, efficient, and general acylating reagents capable of selectivity when chelation is possible. High yields of various esters, amides and thioesters are quickly obtainable and the products are easy to isolate in high purity. The method is readily used under multiple parallel synthesis conditions and is readily scaleable.

Cite this article as:

Gentry J. Elmer, Telikepalli Hanumaiah, Srinivas Pusuluri and Mitscher A. Lester, Tetraacyldiborates: Selective and Efficient Acylation Reagents Suitable for Multiple Parallel Synthetic Applications, Combinatorial Chemistry & High Throughput Screening 2003; 6 (2) . https://dx.doi.org/10.2174/1386207033329797