Abstract
Metallic surfaces and particles can have dramatic effects on fluorescence, including localized excitation, increased quantum yields, increased photostability and increased distances for resonance energy transfer (RET), and directional emission. While all these effects have not yet been realized in a single system, metal-enhanced fluorescence promises to provide the next generation of high sensitivity fluorescence assays for low copy number detection of biochemical species.
Keywords: Metal-Enhanced, Fluorescence, photostability, biochemical species
Combinatorial Chemistry & High Throughput Screening
Title: Metal-Enhanced Fluorescence: Potential Applications in HTS
Volume: 6 Issue: 2
Author(s): Chris D. Geddes, Ignacy Gryczynski, Joanna Malicka, Zygmunt Gryczynski and Joseph R. Lakowicz
Affiliation:
Keywords: Metal-Enhanced, Fluorescence, photostability, biochemical species
Abstract: Metallic surfaces and particles can have dramatic effects on fluorescence, including localized excitation, increased quantum yields, increased photostability and increased distances for resonance energy transfer (RET), and directional emission. While all these effects have not yet been realized in a single system, metal-enhanced fluorescence promises to provide the next generation of high sensitivity fluorescence assays for low copy number detection of biochemical species.
Export Options
About this article
Cite this article as:
Geddes D. Chris, Gryczynski Ignacy, Malicka Joanna, Gryczynski Zygmunt and Lakowicz R. Joseph, Metal-Enhanced Fluorescence: Potential Applications in HTS, Combinatorial Chemistry & High Throughput Screening 2003; 6 (2) . https://dx.doi.org/10.2174/1386207033329760
DOI https://dx.doi.org/10.2174/1386207033329760 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers