Abstract
Steroid and its derivatives have been proved to have important and diverse biological functions, which present the wide spectrum of biological activities such as antitumor, antiviral, antibacterial, antimicrobial, antifungal, antioxidant, insecticidal, aromatase inhibitors, 5α-reductase inhibitors and neuromuscular blocking agents etc. Versatile features of steroid-derived compounds have emerged, so the aim of the present paper is to review the recent advances of steroid-based derivatives mainly focused on their structures and biological applications, which can be employed for further development to discover potential drug candidates.
Keywords: Biological properties, derivatives, diversity, recent progress, steroid, structure.
Graphical Abstract
Mini-Reviews in Medicinal Chemistry
Title:Recent Progress of Novel Steroid Derivatives and Their Potential Biological Properties
Volume: 18 Issue: 9
Author(s): Shaoyong Ke*
Affiliation:
- National Biopesticide Engineering Technology Research Center, Hubei Biopesticide Engineering Research Center, Hubei Academy of Agricultural Sciences, Wuhan 430064,China
Keywords: Biological properties, derivatives, diversity, recent progress, steroid, structure.
Abstract: Steroid and its derivatives have been proved to have important and diverse biological functions, which present the wide spectrum of biological activities such as antitumor, antiviral, antibacterial, antimicrobial, antifungal, antioxidant, insecticidal, aromatase inhibitors, 5α-reductase inhibitors and neuromuscular blocking agents etc. Versatile features of steroid-derived compounds have emerged, so the aim of the present paper is to review the recent advances of steroid-based derivatives mainly focused on their structures and biological applications, which can be employed for further development to discover potential drug candidates.
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Cite this article as:
Ke Shaoyong*, Recent Progress of Novel Steroid Derivatives and Their Potential Biological Properties, Mini-Reviews in Medicinal Chemistry 2018; 18 (9) . https://dx.doi.org/10.2174/1389557517666171003103245
DOI https://dx.doi.org/10.2174/1389557517666171003103245 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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