Abstract
Phthalocyanines exhibit a number of unique properties that make them of great interest in different scientific and technological areas. One of the most promising fields is the use of metallo phthalocyanine derivatives as photosensitizers for Photodynamic Therapy (PDT). Using PDT against cancer involves the irradiation of tumors with visible light following selective uptake of a photosensitizer by the tumor tissue. This review briefly summarizes the photophysical, photochemical and synthetic aspects of phthalocyanines compounds, evaluating their application for PDT.
Keywords: phthalocyanines, photodynamic therapy, metallo phthalocyanine derivative, pdt
Current Organic Chemistry
Title: Synthesis, Photophysical and Photochemical Aspects of Phthalocyanines for Photodynamic Therapy
Volume: 7 Issue: 2
Author(s): Antonio C. Tedesco, Jeane C. G. Rotta and Claure N. Lunardi
Affiliation:
Keywords: phthalocyanines, photodynamic therapy, metallo phthalocyanine derivative, pdt
Abstract: Phthalocyanines exhibit a number of unique properties that make them of great interest in different scientific and technological areas. One of the most promising fields is the use of metallo phthalocyanine derivatives as photosensitizers for Photodynamic Therapy (PDT). Using PDT against cancer involves the irradiation of tumors with visible light following selective uptake of a photosensitizer by the tumor tissue. This review briefly summarizes the photophysical, photochemical and synthetic aspects of phthalocyanines compounds, evaluating their application for PDT.
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Cite this article as:
Tedesco C. Antonio, Rotta C. G. Jeane and Lunardi N. Claure, Synthesis, Photophysical and Photochemical Aspects of Phthalocyanines for Photodynamic Therapy, Current Organic Chemistry 2003; 7 (2) . https://dx.doi.org/10.2174/1385272033373076
DOI https://dx.doi.org/10.2174/1385272033373076 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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