Abstract
Background: This review updates the field of enantioselective organocatalytic Michael reactions performed in aqueous media, covering the literature since the beginning of 2013.
Conclusion: From a green chemistry perspective, this review shows that significant efforts have been recently devoted to the development of these reactions in water and in aqueous media.
Keywords: Asymmetric Michael reactions, organocatalysis, aqueous media, water, green chemistry, chirality.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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