Pharmacological Treatment of Vagal Hyperactivity, a Rare but Potentially Fatal Cause of Sudden Cardiac Death

Title:Pharmacological Treatment of Vagal Hyperactivity, a Rare but Potentially Fatal Cause of Sudden Cardiac Death

Volume: 18 Issue: 6

Author(s): Bassareo Pier Paolo*, Cocco Daniele, Bassareo Valentina, Bandino Stefano and Mercuro Giuseppe

Affiliation:

• Department of Medical Sciences ,Italy

Keywords: Blood pressure, bradycardia, hyperactivity, reflex vagal hypertonia, sudden death, therapy.

Abstract: Vasovagal reaction, resulting in bradycardia and/or hypotension in response to a number of stimuli, is usually self-limiting, but potentially life-threatening exceptions have been described. Pharmacological treatment of proven efficacy is still lacking and the administered compounds are often chosen on the basis of either case reports or outdated small studies with a short-term follow up. In refractory cases, pacemaker implantation may be considered, although no responder patients represent a severe challenge for clinicians. The aim of this review is to examine the state of the art about this controversial issue.

Cite this article as:

Paolo Pier Bassareo *, Daniele Cocco , Valentina Bassareo , Stefano Bandino and Giuseppe Mercuro , Pharmacological Treatment of Vagal Hyperactivity, a Rare but Potentially Fatal Cause of Sudden Cardiac Death, Mini-Reviews in Medicinal Chemistry 2018; 18 (6) . https://dx.doi.org/10.2174/1389557517666170707102040