Natural Product-Like and Other Biologically Active Heterocyclic Libraries Using Solid-Phase Techniques in the Post-Genomic Era

Title: Natural Product-Like and Other Biologically Active Heterocyclic Libraries Using Solid-Phase Techniques in the Post-Genomic Era

Volume: 6 Issue: 7

Author(s): K. Knepper, C. Gil and S. Brase

Affiliation:

Keywords: combinatorial synthesis, total synthesis, natural product, solid-phase, heterocycles, high throughput screening, genomic

Abstract: High-throughput technologies allow the selection of new biological targets for drug discovery in the post-genomic era. These tools increase the need of new methods to rapidly obtain potent small molecules and natural products to discover new lead structures. In particular, the solid-phase synthesis offers a great potential to obtain large compound sets.

Cite this article as:

Knepper K., Gil C. and Brase S., Natural Product-Like and Other Biologically Active Heterocyclic Libraries Using Solid-Phase Techniques in the Post-Genomic Era, Combinatorial Chemistry & High Throughput Screening 2003; 6 (7) . https://dx.doi.org/10.2174/138620703771981232