Model-dependent Small-angle Scattering for the Study of Complex Organic Materials

Title:Model-dependent Small-angle Scattering for the Study of Complex Organic Materials

Volume: 22 Issue: 8

Author(s): Andrew R. McCluskey and Karen J. Edler*

Affiliation:

• Department of Chemistry, University of Bath, Claverton Down, Bath,United Kingdom

Keywords: SAXS, SANS, peptides, polymers, micelles, surfactants, scattering, analysis, model-dependent.

Abstract: Background: Small-angle scattering (SAS) is a powerful technique capable of determining the sample averaged structure of systems within sizes ranging from 1 nm to ~500 nm. This is particularly useful when applied to the study of self-assembled organic systems.

Objective: This review article introduces the method of model-dependent analysis of small angle scattering.

Method: The underlying mathematical constructs on which model-dependent analysis is based are introduced; these are developed further in practical terms through examples from recent literature.

Results: Basic analysis methods are shown, in addition to more complex models for shapes and inter-particle interactions. These are demonstrated with examples from three areas of organic chemistry; small molecule surfactants, polymers, and peptides.

Conclusion: The importance and applicability of small-angle scattering model-dependent analysis of complex organic molecules have been shown through both the fundamental mathematics and literature examples.

Cite this article as:

McCluskey R. Andrew and Edler J. Karen*, Model-dependent Small-angle Scattering for the Study of Complex Organic Materials, Current Organic Chemistry 2018; 22 (8) . https://dx.doi.org/10.2174/1875692115666170612104439