2,3-Dichloro-1,4-Naphthoquinone in Organic Synthesis: Recent Advances

Title:2,3-Dichloro-1,4-Naphthoquinone in Organic Synthesis: Recent Advances

Volume: 14 Issue: 5

Author(s): Luana da S. M. Forezi, Mariana F. C. Cardoso, Dora C. S. Costa, Fernando de C. da Silva and Vitor F. Ferreira*

Affiliation:

• Universidade Federal Fluminense, Departamento de Química Orgânica, Programa de Pós- Graduação em Química, Outeiro de São João Baptista, 24020-141 Niterói, RJ,Brazil

Keywords: Quinones, synthetic applications, biological activity, heterocycles, cyclization reactions, nucleophilic substitutions, napthoquinone.

Abstract: 2,3-Dichloro-1,4-naphthoquinone is a special naphthoquinone with four electrophilic sites, useful for applications in organic synthesis and preparation of a diverse new compounds, such as 2,3-substituted derivatives and heterocycles, including those with the core naphthoquinone structure fused. It has also been used for the preparation of compounds for evaluation against several biological targets. This review will describe the most recent applications of 2,3-dichloro-1,4-naphthoquinone in organic synthesis.

Cite this article as:

Forezi da S. M. Luana, Cardoso F. C. Mariana, Costa C. S. Dora , da Silva de C. Fernando and Ferreira F. Vitor *, 2,3-Dichloro-1,4-Naphthoquinone in Organic Synthesis: Recent Advances, Mini-Reviews in Organic Chemistry 2017; 14 (5) . https://dx.doi.org/10.2174/1570193X14666170518125507