Abstract
Purpose: The purpose of this study was to compare the value of 99mTc-octreotide scintigraphy and planar X-ray mammography in the diagnosis of breast cancer.
Methods: A total of 65 patients with suspected breast cancer were enrolled. All patients underwent 99mTc-octreotide scintigraphy and planar X-ray mammography. The diagnostic efficiencies of 99mTc-octreotide scintigraphy and planar X-ray mammography were compared based on postsurgery pathology.
Results: The sensitivities of 99mTc-octreotide scintigraphy and planar X-ray mammography in the diagnosis of breast cancer were 90.6% and 66.0%, respectively. The specificities were 00% and 41.7%, while the accuracies were 91.4% and 66.7%, respectively. When 99mTc-octreotide scintigraphy was combined with planar X-ray mammography, the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for breast cancer were 96.2%, 100%, 94.1%, 87.9%, and 36.4%, respectively.
Conclusion: The diagnostic efficiency of 99mTc-octreotide scintigraphy for breast cancer is superior to that of planar X-ray mammography. When combined with planar X-ray mammography, the diagnostic efficiency of 99mTc-octreotide scintigraphy for breast cancer is further increased.
Keywords: 99mTc-octreotide scintigraphy, X-ray mammography, breast cancer, somatostatin, receptor, invasive ductal carcinoma.
Graphical Abstract
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