Cationic Transfection Lipids

Title: Cationic Transfection Lipids

Volume: 10 Issue: 14

Author(s): Dexi Liu, Tan Ren and Xiang Gao

Affiliation:

Keywords: cationic lipids, gene delivery, liposomes, nonviral vectors, transfection

Abstract: This review focuses on the recent developments in study of cationic lipids as carriers for DNA delivery. Emphasis is placed on a class of compounds as exemplifies by their similarity in structures and transfection activities. The technical aspects are also reviewed on how to prepare DNA-lipid complexes and to perform transfection. A brief discussion of the current views on the mechanism of cationic lipid-mediated DNA transfer is intended to provide new prospects for future developments and further improvement of the current systems.

Cite this article as:

Liu Dexi, Ren Tan and Gao Xiang, Cationic Transfection Lipids, Current Medicinal Chemistry 2003; 10 (14) . https://dx.doi.org/10.2174/0929867033457386