Abstract
Background: Intracerebral hemorrhage is one of the most common injuries in vehicle accidents. The aim of this paper is to survey the injury mechanism of intracerebral hemorrhage in vehicle accidents, including contusion, subarachnoid hemorrhage (SAH), subdural hematoma (SDH) and diffuse axonal injury (DAI).
Methods: A condensed overview is given based on the published studies in biomechanical studies on intracerebral hemorrhage. Animal tests, cadaver tests, accident investigations and numerical simulation are the main method used for the mechanism studies. Results: Angular velocity and acceleration can be used to predict these injuries and they are the main causation of DAI. Intracranial pressure is the main causation of coup/contrecoup contusion. Shear stress and strain contribute to the rupture of bridging veins that result in SDH, SAH. Conclusion: Injury mechanism of intracerebral hemorrhage in vehicle accidents is complicated that with multiple causations. In-depth works need to be carried out in mechanism studies especially for child head injuries.Keywords: Intracerebral hemorrhage, brain injury, vehicle accident, passive safety, subarachnoid hemorrhage (SAH), subdural hematoma (SDH).
Current Pharmaceutical Design
Title:A Review on Injury Mechanism of Intracerebral Hemorrhage in Vehicle Accidents
Volume: 23 Issue: 15
Author(s): Fan Li*, Honggeng Li, Zhi Xiao, Ronggui Lu, Zhiteng Zhang, Haiyun Zhu and Lihai Ren
Affiliation:
- Arts et Metiers, ParisTech, Paris,France
Keywords: Intracerebral hemorrhage, brain injury, vehicle accident, passive safety, subarachnoid hemorrhage (SAH), subdural hematoma (SDH).
Abstract: Background: Intracerebral hemorrhage is one of the most common injuries in vehicle accidents. The aim of this paper is to survey the injury mechanism of intracerebral hemorrhage in vehicle accidents, including contusion, subarachnoid hemorrhage (SAH), subdural hematoma (SDH) and diffuse axonal injury (DAI).
Methods: A condensed overview is given based on the published studies in biomechanical studies on intracerebral hemorrhage. Animal tests, cadaver tests, accident investigations and numerical simulation are the main method used for the mechanism studies. Results: Angular velocity and acceleration can be used to predict these injuries and they are the main causation of DAI. Intracranial pressure is the main causation of coup/contrecoup contusion. Shear stress and strain contribute to the rupture of bridging veins that result in SDH, SAH. Conclusion: Injury mechanism of intracerebral hemorrhage in vehicle accidents is complicated that with multiple causations. In-depth works need to be carried out in mechanism studies especially for child head injuries.Export Options
About this article
Cite this article as:
Li Fan*, Li Honggeng, Xiao Zhi, Lu Ronggui, Zhang Zhiteng, Zhu Haiyun and Ren Lihai, A Review on Injury Mechanism of Intracerebral Hemorrhage in Vehicle Accidents, Current Pharmaceutical Design 2017; 23 (15) . https://dx.doi.org/10.2174/1381612823666161118144829
DOI https://dx.doi.org/10.2174/1381612823666161118144829 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Progress in COX-2 Inhibitors: A Journey So Far
Current Medicinal Chemistry Pharmacological Activity of Cardiovascular Agents from Herbal Medicine
Cardiovascular & Hematological Agents in Medicinal Chemistry Targeting Heat Shock Protein 90 for Malaria
Mini-Reviews in Medicinal Chemistry Calcitonin Gene-Related Family Peptides in Vascular Adaptations, Uteroplacental Circulation, and Fetal Growth
Current Vascular Pharmacology Optimized Methods for In Vitro and In Vivo Anti-Inflammatory Assays and Its Applications in Herbal and Synthetic Drug Analysis
Mini-Reviews in Medicinal Chemistry Host-Pathogen Interactions and the Pathological Consequences of Acute Systemic Candida albicans Infections in Mice
Current Drug Targets Cushing's Syndrome and Steroid Dementia
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) Patent Annotations
Recent Patents on CNS Drug Discovery (Discontinued) A Review on Expedient Assets of Polymers Employed in Novel Topical Formulation for Successful Treatment of Arthritis
Current Applied Polymer Science Neuroinflammation and its Modulation by Flavonoids
Endocrine, Metabolic & Immune Disorders - Drug Targets Neurotrophic Factors in Combination: A Possible new Therapeutic Strategy to Influence Pathophysiology of Spinal Cord Injury and Repair Mechanisms
Current Pharmaceutical Design Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option
Current Topics in Medicinal Chemistry miR-15b Suppression of Bcl-2 Contributes to Cerebral Ischemic Injury and is Reversed by Sevoflurane Preconditioning
CNS & Neurological Disorders - Drug Targets Glutathione-Related Factors and Oxidative Stress in Autism, A Review
Current Medicinal Chemistry Understanding Nutritional Interventions and Physical Exercise in Non-Alcoholic Fatty Liver Disease
Current Molecular Medicine An Outline of the Historical and Clinical Aspects of Catatonic Schizophrenia
Current Psychiatry Reviews PPAR-γ Agonists in Polycystic Kidney Disease with Frequent Development of Cardiovascular Disorders
Current Molecular Pharmacology Why is the Inhibition of the Renin-Angiotensin System Effective for Preventing Cardiac Events in Patients with Coronary Risk Factors or Coronary Artery Disease?
Current Cardiology Reviews Symmetry Plane Detection in Brain Image Analysis: A Survey
Current Medical Imaging VEGF Signaling in Cancer Treatment
Current Pharmaceutical Design