Computational Modelling of Magnetic Nanoparticle Properties and In Vivo Responses

doi:10.2174/0929867323666161018141902

摘要

纳米粒被发现有很多应用在医学和其他像光子领域。在医学方面磁性纳米粒相比非磁性硬纳米粒有额外的优势，因为具有磁性使他们是在治疗中温热应用和敏感诊断影像应用的理想材料。我回顾了在磁性能力计算模型关于磁性纳米的特异性方面的文献。这种模型有加速磁性纳米粒在医学设计方面应用的可能性。目前的文献涉及的磁纳米粒子的建模诱导异常细胞的热疗，有着显着的作用目的，旨在模拟和预测性能的医疗成像和靶向交付的药物和基因疗法。

关键词: 磁性纳米粒，癌症，计算模型，无限元分析，细胞摄入，超高温，释放。

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Current Medicinal Chemistry

Title:Computational Modelling of Magnetic Nanoparticle Properties and In Vivo Responses

Volume: 24 Issue: 5

关键词: 磁性纳米粒，癌症，计算模型，无限元分析，细胞摄入，超高温，释放。

摘要: Nanoparticles are finding many applications in medicine and other fields like photonics. Magnetic nanoparticles have additional advantages in medicine over non-magnetic hard nanoparticles, as their magnetic properties make them ideal for hyperthermic applications in therapy and for sensitive diagnostic imaging applications. I review the literature on computational models of the magnetic properties of nanoparticles specifically. Such models have the potential to accelerate the design of magnetic nanoparticles for medical applications. Much of the current literature relates to the modelling of magnetic nanoparticles for inducing hyperthermia in aberrant cells, with significant bodies of work aimed at simulating and predicting properties for medical imaging and targeted delivery of drugs and gene therapies.

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Computational Modelling of Magnetic Nanoparticle Properties and In Vivo Responses, Current Medicinal Chemistry 2017; 24 (5) . https://dx.doi.org/10.2174/0929867323666161018141902

DOI https://dx.doi.org/10.2174/0929867323666161018141902	Print ISSN 0929-8673
Publisher Name Bentham Science Publisher	Online ISSN 1875-533X