摘要
男性异常基因家族包括3个成员,叫做mab21l1、mab21l2和mab21l3。自从它们在C.线虫中首次发现,mab21l1和mab21l2的同系物已经在果蝇、斑马鱼、非洲爪蟾、小鸡、老鼠和人类中发现。许多研究揭示了mab21基因家族成员--mab2111和mab2112--在控制眼睛发育中起着重要作用。这里,我们回顾了mab基因在控制眼睛发育中的功能。
关键词: Mab21
Current Molecular Medicine
Title:The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development
Volume: 16 Issue: 7
Author(s): Z.-X. Huang, J.-W. Xiang, L. Zhou, Q. Nie, L. Wang, Z.-G. Chen, X.-H. Hu, Y. Xiao, W.-J. Qing, Y.-F. Liu, Q. Sun, X.-C. Tang and , F.-Y. Liu, Z.-W. Luo, W.-B. Liu, D. W.-C. Li
Affiliation:
关键词: Mab21
摘要: The male abnormal gene family contains 3 members, named mab21l1, mab21l2 and mab21l3. Since their first discovery in C. elegans, homologues of mab21l1 and mab21l2 have been found in Drosophila, Zebrafish, Xenopus, chicken, mouse and human. A number of studies have revealed that mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. Here, we review the functions of the mab genes in regulating ocular development.
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Z.-X. Huang, J.-W. Xiang, L. Zhou, Q. Nie, L. Wang, Z.-G. Chen, X.-H. Hu, Y. Xiao, W.-J. Qing, Y.-F. Liu, Q. Sun, X.-C. Tang and , F.-Y. Liu, Z.-W. Luo, W.-B. Liu, D. W.-C. Li , The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development, Current Molecular Medicine 2016; 16 (7) . https://dx.doi.org/10.2174/1566524016666160824150729
DOI https://dx.doi.org/10.2174/1566524016666160824150729 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
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