A New Direction in Ophthalmic Development: Nanoparticle Drug Delivery Systems

Title:A New Direction in Ophthalmic Development: Nanoparticle Drug Delivery Systems

Volume: 22 Issue: 41

Author(s): Velichka Yordanova Andonova

Affiliation:

Keywords: Ocular absorption, ocular drug delivery, nanoparticles, proniosomes, micro-needles.

Abstract: The purpose of each dosage form is to provide an optimal therapeutic effect with a minimum dose and with minimal side effects. This is particularly relevant for drugs that require systemic administration, higher dosing and/or show lower bioavailability. Тhe eye as an anatomical structure is an extremely protected organ. In this regard, providing an optimal bioavailability in the eye tissues, resulting in the desired therapeutic effect represents a major challenge. This is especially true for the treatment of diseases, affecting the posterior segment after topically administered drug formulations. The use of nano- and microcarriers of drug substances may be an appropriate technological approach, to provide a high bioavailability of the drug substance for a certain interval of time at the right place.

Cite this article as:

Andonova Yordanova Velichka, A New Direction in Ophthalmic Development: Nanoparticle Drug Delivery Systems, Current Pharmaceutical Design 2016; 22 (41) . https://dx.doi.org/10.2174/1381612822666160813234723