A Review on Pharmacological Properties of Coumarins

Title:A Review on Pharmacological Properties of Coumarins

Volume: 18 Issue: 2

Author(s): Devulapally Srikrishna, Chandraiah Godugu and Pramod Kumar Dubey*

Affiliation:

• Department of Chemistry, Jawaharlal Nehru Technological University College of Engineering, Kukatpally, Hyderabad 500 085,India

Keywords: Anticancer, anticonvulsant, anti-inflammatory, antimicrobial, antioxidant, coumarin, MAO inhibitory, pharmacological properties.

Abstract: The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in many natural products, displays diverse pharmacological properties. It has attracted the attention of chemists and medicinal chemists for decades. Many molecules based on the coumarin ring system have been described utilizing innovative synthetic methods. These synthetic routes have led to interesting analogues of coumarins which possess pharmacological activities like anti-HIV, antimicrobial, antiinflammatory, anticancer, anti-TB, anticonvulsant and MAO inhibitory properties. Details of these studies, correlating structure with biological activity are described in this review.

Cite this article as:

Srikrishna Devulapally, Godugu Chandraiah and Dubey Kumar Pramod*, A Review on Pharmacological Properties of Coumarins, Mini-Reviews in Medicinal Chemistry 2018; 18 (2) . https://dx.doi.org/10.2174/1389557516666160801094919