摘要
糖尿病患者的皮肤和角膜伤口是一个重要的医疗负担。微小核糖核酸是小的非编码核糖核酸,在转录后水平调控蛋白基因的表达。研究发现微小核糖核酸参与创面愈合的各个阶段。微小核糖核酸失调可导致受损或糖尿病患者皮肤和角膜伤口愈合延迟。在这里,我们提出了一个涉及糖尿病皮肤和角膜伤口愈合的微小核糖核酸的文献以及那些作为糖尿病伤口愈合的潜在生物标志物的综合概述。
关键词: 微小核糖核酸,伤口愈合,皮肤,角膜,糖尿病的发病机制。
Current Molecular Medicine
Title:Small RNAs Play Big Roles: MicroRNAs in Diabetic Wound Healing
Volume: 16 Issue: 6
Author(s): F. Fahs, X.-L. Bi, F.-S. Yu, L. Zhou, Q.-S. Mi
Affiliation:
关键词: 微小核糖核酸,伤口愈合,皮肤,角膜,糖尿病的发病机制。
摘要: Skin and corneal wounds in diabetics are a major healthcare burden. MicroRNAs are small, non-coding RNAs that post-transcriptionally regulate the expression of proteincoding genes. Studies have identified microRNAs involved in all phases of wound healing. The dysregulation of microRNAs can contribute to impaired or delayed skin and corneal wound healing in diabetics. Here, we present a comprehensive review of the literature involving microRNAs in diabetic skin and corneal wound healing as well as those serving as potential biomarkers for diabetic wound healing.
Export Options
About this article
Cite this article as:
F. Fahs, X.-L. Bi, F.-S. Yu, L. Zhou, Q.-S. Mi , Small RNAs Play Big Roles: MicroRNAs in Diabetic Wound Healing, Current Molecular Medicine 2016; 16 (6) . https://dx.doi.org/10.2174/1566524016666160607091156
DOI https://dx.doi.org/10.2174/1566524016666160607091156 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Perspectives on New Synthetic Curcumin Analogs and their Potential Anticancer Properties
Current Pharmaceutical Design Oxidative-Nitrosative Stress as a Contributing Factor to Cardiovascular Disease in Subjects with Diabetes
Current Vascular Pharmacology Extra Virgin Olive Oils Polyphenols: Biological Activities
Current Pharmaceutical Design Human Cognitive and Neuro-Psychiatric Bio-Markers in the Cardiac Peri-Operative Patient
Current Molecular Medicine Differential Action of Phytochemicals on Platelet Apoptosis: A Biological Overview
Current Medicinal Chemistry Artepillin C Induces Selective Oxidative Stress and Inhibits Migration and Invasion in a Comprehensive Panel of Human Cervical Cancer Cell Lines
Anti-Cancer Agents in Medicinal Chemistry Stem Cell Therapy for the Treatment of Myocardial Infarction
Current Pharmaceutical Design Increased Content of Free Phenolic Compounds and Antioxidant Activity of Grape Pomace Cultivated with Three Different β-glucosidase Fungi Producers
Current Bioactive Compounds Phytochemical Investigation and Quantitative Analysis of the Fatty Acids and Sterol Compounds of Seven Pharmaceutical valuable Seeds
Current Pharmaceutical Analysis Endothelial Progenitor Cells in Prehypertension
Current Pharmaceutical Design Lipoprotein(a) is a Therapeutic Target for Cardiovascular Disease
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Insulin Resistance as a Proinflammatory State: Mechanisms, Mediators, and Therapeutic Interventions
Current Drug Targets Harnessing Polypharmacology with Computer-Aided Drug Design and Systems Biology
Current Pharmaceutical Design Semi-Quantitative Ultrasonographic Evaluation of NAFLD
Current Pharmaceutical Design Effects of Different Process and Machine Parameters on Physical Properties of Rice Flour, Corn Flour and Deoiled Rice Bran Extruded Product
Current Nutrition & Food Science New Therapeutic Aspects of Inflammatory Cardiomyopathy
Current Pharmaceutical Design Mitochondrial Therapeutics for Cardioprotection
Current Pharmaceutical Design Polydeoxyribonucleotide (PDRN): A Safe Approach to Induce Therapeutic Angiogenesis in Peripheral Artery Occlusive Disease and in Diabetic Foot Ulcers
Cardiovascular & Hematological Agents in Medicinal Chemistry Impact of Pre-Diabetes and Diabetes on Cardiovascular Outcomes
Current Vascular Pharmacology Subject Index To Volume 8
Current Pharmaceutical Design