内皮细胞生物学的未来靶点：内皮细胞-间质转化

Title:Future Targets in Endothelial Biology: Endothelial Cell to Mesenchymal Transition

Volume: 17 Issue: 15

Author(s): Pei-Yu Chen, Michael Simons

Affiliation:

关键词: 内皮细胞；内皮细胞-间质转化；EndMT；转化生长因子-β；成纤维细胞生长因子

摘要: Endothelial to mesenchymal transition (EndMT) is a poorly understood phenomenon that results in normal endothelial cells acquiring a mesenchymal phenotype. EndMT has been observed in a number of pathological conditions, from cancer to fibrosis to cardiovascular disease and the process itself may play an important mechanistic role in the development of these disease states.

Cite this article as:

Pei-Yu Chen, Michael Simons , Future Targets in Endothelial Biology: Endothelial Cell to Mesenchymal Transition, Current Drug Targets 2016; 17 (15) . https://dx.doi.org/10.2174/1389450117666160502151308