Abstract
Ephedra heterocycles are well known due to their biological activity, and they have been widely used in asymmetric synthesis during the last decades. To our knowledge no review about ephedra heterocycles has appeared in the literature. In this paper, the synthetic methodology to access chiral heterocycles derived from ephedra alkaloids is discussed. Some of them have displayed biological activity and others have been used as asymmetric inductors, clearly the ephedra alkaloids are potential candidates to be used in both areas.
Keywords: heterocyclic compounds, ephedrines, ephedra heterocycles, asymmetric inductors, ephedra alkaloids
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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