摘要
桑色素是一种天然多酚,最初从桑科植物中分离而来,可以从许多植物的叶、果实、茎和枝条中提取出来。一些证据表明,桑色素可能对一些人类疾病起有效作用。事实上,桑色素通过调节多种酶的活性,具有抗氧化、抗糖尿病、抗炎、抗肿瘤、降血压、抗菌、降尿酸和神经保护作用。在某些情况下,桑色素显示系统保护作用,减少一些药物的副作用而能不影响其功能。此外,在体外和体内研究表明,桑色素具有非常低的毒性和慢性给药耐受性良好。所有这些研究结果表明,桑色素可以单独用药或与其他药物联合用药,以预防许多人类疾病。
关键词: 桑色素、黄酮、多酚、天然药物、抗氧化、抗糖尿病、抗炎。
Current Medicinal Chemistry
Title:Morin: A Promising Natural Drug
Volume: 23 Issue: 8
Author(s): Anna Caselli, Paolo Cirri, Alice Santi and Paolo Paoli
Affiliation:
关键词: 桑色素、黄酮、多酚、天然药物、抗氧化、抗糖尿病、抗炎。
摘要: Morin is a natural polyphenol, originally isolated from members of the Moraceae family that can be extracted from leaves, fruits, stems and branches of numerous plants. Several evidence have demonstrated that Morin could have a beneficial effect on several human diseases. In fact, Morin exerts antioxidant, antidiabetic, anti-inflammatory, antitumoral, antihypertensive, antibacterial, hypouricemic, and neuroprotective effects, by modulating the activity of many enzymes. In some cases, Morin shows a systemic protective action, reducing negative side effects of several drugs, without interfering with their functions. In addition, in vitro and in vivo studies demonstrated that Morin exhibits very low toxicity levels and its chronic administration is well tolerated. All these findings suggest that Morin could be used, either alone or in combination with other drugs, to prevent many human pathologies.
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Cite this article as:
Anna Caselli, Paolo Cirri, Alice Santi and Paolo Paoli , Morin: A Promising Natural Drug, Current Medicinal Chemistry 2016; 23 (8) . https://dx.doi.org/10.2174/0929867323666160106150821
DOI https://dx.doi.org/10.2174/0929867323666160106150821 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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