Restless Legs Syndrome After Single Low Dose Quetiapine Administration

Title:Restless Legs Syndrome After Single Low Dose Quetiapine Administration

Volume: 11 Issue: 2

Author(s): Ahmet Z. Soyata, Fahri Celebi and Lutfi I. Yargc

Affiliation:

Keywords: Restless legs syndrome, clozapine, psychotropic drugs, quetiapine, risperidone.

Abstract: Restless legs syndrome is an underdiagnosed sensori-motor disorder and psychotropic drugs are one of the main secondary causes of the illness. The most common psychotropic agents that cause restless legs syndrome are antidepressants; however, antipsychotics have also been reported to induce restless legs syndrome. The prevalence, vulnerability factors and the underlying mechanism of antipsychotic-induced restless legs syndrome are unclear. A possible explanation is that dopaminergic blockade is the main precipitator of the syndrome. Quetiapine-induced restless legs syndrome is another point of interest because of its low binding to D2 receptors. We herein report the case of a restless legs syndrome that emerged after a single low dose quetiapine administration.

Cite this article as:

Z. Soyata Ahmet, Celebi Fahri and I. Yargc Lutfi, Restless Legs Syndrome After Single Low Dose Quetiapine Administration, Current Drug Safety 2016; 11 (2) . https://dx.doi.org/10.2174/1574886311207040298