Synthesis, Structural Characterization of a Novel Ferrocene Derivative and Preliminarily Anticancer Activity

Title:Synthesis, Structural Characterization of a Novel Ferrocene Derivative and Preliminarily Anticancer Activity

Volume: 12 Issue: 5

Author(s): Jianping Yong, Xiaoyuan Wu, Jianzhen Liao, Canzhong Lu and Xiaolong Liu

Affiliation:

Keywords: Ferrocene derivative, synthesis, characterization, NMR, XRD, anticancer activity.

Abstract: A novel structure of ferrocene derivative 1 was synthesized with cyanuric chloride and ferrocenemethanol as starting materials. The synthesized compound was fully characterized using 1H NMR, 13C NMR, MS and XRD. Subsequently, the in vitro anticancer effect against A549, HCT116 and MCF-7 cell lines was preliminarily evaluated by the MTT method. The result showed that this compound exhibits good cytotoxic effect on A549, HCT116 and MCF-7 cell lines.

Cite this article as:

Yong Jianping, Wu Xiaoyuan, Liao Jianzhen, Lu Canzhong and Liu Xiaolong, Synthesis, Structural Characterization of a Novel Ferrocene Derivative and Preliminarily Anticancer Activity, Medicinal Chemistry 2016; 12 (5) . https://dx.doi.org/10.2174/1573406412666151112125345