Beta-Blockers: Current State of Knowledge and Perspectives

Title:Beta-Blockers: Current State of Knowledge and Perspectives

Volume: 16 Issue: 1

Author(s): Magdalena Ogrodowczyk, Katarzyna Dettlaff and Anna Jelinska

Affiliation:

Keywords: Activity, application, aryloxyaminopropanol derivatives, beta-blockers, structure.

Abstract: It has been over half a century since propranolol, the first beta-blocker, was developed for medical treatment. Since that time a large number of compounds from this group have been synthesised and many are now in clinical use. The structure, function, pharmacokinetics, and mechanism of beta-blockers have been established. The possibilities for their use in treating different conditions continue to evolve. Since the discovery of later generation beta-blockers, such as carvedilol and nebivolol, the search for new compounds continues, and may include known substances with betablocking properties which could extend their therapeutic potential.

Cite this article as:

Ogrodowczyk Magdalena, Dettlaff Katarzyna and Jelinska Anna, Beta-Blockers: Current State of Knowledge and Perspectives, Mini-Reviews in Medicinal Chemistry 2016; 16 (1) . https://dx.doi.org/10.2174/1389557515666151016125948