Natural Products and Cancer Stem Cells

Title:Natural Products and Cancer Stem Cells

Volume: 21 Issue: 38

Author(s): Cristina Marucci, Gaia Fumagalli, Francesco Calogero, Alessandra Silvani, Michael S. Christodoulou, Nadine Martinet and Daniele Passarella

Affiliation:

Keywords: Natural products, drug discovery, cancer stem cells.

Abstract: The development of modern technologies casts a new light on the natural products as an invaluable source of lead compounds that could guide drug discovery. Cancer stem cells are a subpopulation of cancer cells with a high clonogenic capacity and the ability to reform the parental tumours upon transplantation. They have been proposed to drive tumorigenesis and metastases. In this review, we present the ability of forty-nine different natural products to influence the biology of cancer stem cells.

Cite this article as:

Marucci Cristina, Fumagalli Gaia, Calogero Francesco, Silvani Alessandra, Christodoulou S. Michael, Martinet Nadine and Passarella Daniele, Natural Products and Cancer Stem Cells, Current Pharmaceutical Design 2015; 21 (38) . https://dx.doi.org/10.2174/1381612821666151002113114